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223922 Atf7

223922

Atf7

activating transcription factor 7

protein-coding

Mus musculus

基因描述

Type Description
Definition activating transcription factor 7

研究结论

Date Results Publications
2020-08-29 12:48:00 ATF7-Dependent Epigenetic Changes Are Required for the Intergenerational Effect of a Paternal Low-Protein Diet. 32197065
2020-01-11 12:10:00 ATF7 is involved in regulating lifespan and stress-induced senescence via p16Ink4a gene transcription. 31294895
2019-08-31 13:09:00 Here, we show that TNF-alpha, which is induced by various psychological stresses, induces the p38-dependent phosphorylation of ATF7, a stress-responsive chromatin regulator, in mouse testicular germ cells. This caused a release of ATF7 from the TERRA gene promoter in the subtelomeric region, which disrupted heterochromatin and induced TERRA. 30407559
2019-07-27 12:37:00 A decrease of ATF7 and telomerase on telomeres in response to stress causes telomere shortening, as observed in ATF7-deficient mice. 29490055
2017-06-03 10:54:00 ATF7 ablation prevents diet-induced obesity and insulin resistance. 27498002

名称对应

Type IDs
Synonymous 1110012F10Rik, 9430065F09Rik, AI549878, C130020M04Rik
Gene
UniProtKB-ID: V9GXN6_MOUSE, Q3TZR9_MOUSE
UniprotKB: V9GXN6, Q3TZR9
UniParc: UPI00001E9F8E, UPI00001E9F92
EMBL: AC137156, AC123870, AK157628
Ensembl: ENSMUSG00000099083
KO: mmu:223922
Nucleutide sequences
EMBL-CDS: BAE34138.1
Ensembl_TRS: ENSMUST00000184906, ENSMUST00000184616, ENSMUST00000184485
Protein sequencees
Ensembl_PRO: ENSMUSP00000139243, ENSMUSP00000139181, ENSMUSP00000139308
RefSeq: NP_001296995.1, NP_001296999.1, NP_001296996.1
Others
UniRef100: UniRef100_Q3TZR9, UniRef100_V9GXN6
UniRef90: UniRef90_Q8R0S1, UniRef90_P17544
UniRef50: UniRef50_P17544
UniGene: Mm.208714, Mm.475149

全选

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研究热度

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