Type | Description |
---|---|
Definition | sterol O-acyltransferase 2 |
Date | Results | Publications |
---|---|---|
2020-02-29 11:30:00 | The study found that Soat2-/- mice fed high-fat, low-cholesterol diet to have less hepatic steatosis, decreased expression of genes involved in de novo lipogenesis and lower hepatic GLUT2. | 30630736 |
2019-08-17 10:14:00 | SOAT2 knockout in NPC1-deficient mice decreases hepatic cholesterol accumulation and improves liver function. | 29878847 |
2019-02-07 17:02:00 | ACAT2 provides core CE of newly secreted VLDL, whereas LCAT adds CE during LDL particle formation | 15805543 |
2019-02-07 17:01:00 | ABCA1, especially in the absence of ACAT2, can have a significant effect on cholesterol absorption, although ACAT2 has a more substantial role in this process than ABCA1 | 16150828 |
2019-02-07 17:00:00 | depletion of hepatic ACAT2-driven cholesterol esterification reveals a non-biliary route for fecal neutral sterol loss | 18281279 |
Type | IDs |
---|---|
Synonymous | ACAT2, D15Wsu97e |
Gene |
UniProtKB-ID:
SOAT2_MOUSE
UniprotKB:
O88908
UniParc:
UPI0000027D31
EMBL:
AF078751,
CH466550,
BC025931
Ensembl:
ENSMUSG00000023045
KO:
mmu:223920
|
Nucleutide sequences |
EMBL-CDS:
EDL04004.1,
AAC64057.1,
AAH25931.1
Ensembl_TRS:
ENSMUST00000023806
|
Protein sequencees |
Ensembl_PRO:
ENSMUSP00000023806
RefSeq:
NP_666176.1
|
Others |
UniRef100:
UniRef100_O88908
UniRef90:
UniRef90_O88908
UniRef50:
UniRef50_O75908-3
UniGene:
Mm.358862
CCDS:
CCDS27872.1
|
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Refseq |
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