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223920 Soat2

223920

Soat2

sterol O-acyltransferase 2

protein-coding

Mus musculus

基因描述

Type Description
Definition sterol O-acyltransferase 2

研究结论

Date Results Publications
2020-02-29 11:30:00 The study found that Soat2-/- mice fed high-fat, low-cholesterol diet to have less hepatic steatosis, decreased expression of genes involved in de novo lipogenesis and lower hepatic GLUT2. 30630736
2019-08-17 10:14:00 SOAT2 knockout in NPC1-deficient mice decreases hepatic cholesterol accumulation and improves liver function. 29878847
2019-02-07 17:02:00 ACAT2 provides core CE of newly secreted VLDL, whereas LCAT adds CE during LDL particle formation 15805543
2019-02-07 17:01:00 ABCA1, especially in the absence of ACAT2, can have a significant effect on cholesterol absorption, although ACAT2 has a more substantial role in this process than ABCA1 16150828
2019-02-07 17:00:00 depletion of hepatic ACAT2-driven cholesterol esterification reveals a non-biliary route for fecal neutral sterol loss 18281279

名称对应

Type IDs
Synonymous ACAT2, D15Wsu97e
Gene
UniProtKB-ID: SOAT2_MOUSE
UniprotKB: O88908
UniParc: UPI0000027D31
EMBL: AF078751, CH466550, BC025931
Ensembl: ENSMUSG00000023045
KO: mmu:223920
Nucleutide sequences
EMBL-CDS: EDL04004.1, AAC64057.1, AAH25931.1
Ensembl_TRS: ENSMUST00000023806
Protein sequencees
Ensembl_PRO: ENSMUSP00000023806
RefSeq: NP_666176.1
Others
UniRef100: UniRef100_O88908
UniRef90: UniRef90_O88908
UniRef50: UniRef50_O75908-3
UniGene: Mm.358862
CCDS: CCDS27872.1

全选

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研究热度

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