| Type | Description |
|---|---|
| Definition | Rap guanine nucleotide exchange factor (GEF) 3 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:33:00 | Epac1 Requires AMPK Phosphorylation to Regulate HMGB1 in the Retinal Vasculature. | 32940662 |
| 2021-02-06 13:59:00 | beta-Adrenergic Receptors/Epac Signaling Increases the Size of the Readily Releasable Pool of Required for Parallel Fiber LTP. | 33046543 |
| 2021-01-09 13:31:00 | Exchange protein directly activated by cAMP (Epac) 1 plays an essential role in stress-induced exercise capacity by regulating PGC-1alpha and fatty acid metabolism in skeletal muscle. | 31955265 |
| 2020-12-19 13:44:00 | Epac1 (Exchange Protein Directly Activated by cAMP 1) Upregulates LOX-1 (Oxidized Low-Density Lipoprotein Receptor 1) to Promote Foam Cell Formation and Atherosclerosis Development. | 33054390 |
| 2020-11-21 13:24:00 | Neuronal Epac1 mediates retinal neurodegeneration in mouse models of ocular hypertension. | 31918438 |
| Type | IDs |
|---|---|
| Synonymous | 2310016P22Rik, 9330170P05Rik, Epac, Epac1 |
| Gene |
UniProtKB-ID:
RPGF3_MOUSE,
Q3UQC2_MOUSE,
Q3TES7_MOUSE,
E9Q2E5_MOUSE
UniprotKB:
Q8VCC8,
Q3UQC2,
Q3TES7,
E9Q2E5
UniParc:
UPI00005B2571,
UPI00004CB0BC,
UPI0001889CCF,
UPI000176165C,
UPI00005AC157
EMBL:
AK034265,
AK142594,
AK169430,
AC104225,
BC020532,
BC020311
Ensembl:
ENSMUSG00000022469
KO:
mmu:223864
|
| Nucleutide sequences |
EMBL-CDS:
BAC28653.1,
AAH20532.1,
AAH20311.1,
BAE25120.1,
BAE41171.1
Ensembl_TRS:
ENSMUST00000129223,
ENSMUST00000126854,
ENSMUST00000128775
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000118148,
ENSMUSP00000116426,
ENSMUSP00000120126
RefSeq:
NP_001344559.1,
XP_036015270.1,
XP_036015269.1,
XP_011243905.1,
XP_036015276.1,
NP_001171281.1,
XP_017172074.1,
XP_030104383.1,
XP_036015274.1,
XP_017172071.1,
XP_036015275.1,
XP_011243904.1,
XP_036015268.1,
XP_030104384.1,
XP_036015273.1,
XP_036015267.1,
XP_036015272.1,
XP_017172072.1,
XP_017172073.1,
NP_001171282.1,
XP_036015271.1,
NP_659099.2
|
| Others |
UniRef100:
UniRef100_Q8VCC8,
UniRef100_Q3TES7,
UniRef100_Q3UQC2,
UniRef100_E9Q2E5
UniRef90:
UniRef90_Q9Z1C8
UniRef50:
UniRef50_Q9Z1C8
UniGene:
Mm.24028
CCDS:
CCDS49714.1,
CCDS37187.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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