| Type | Description |
|---|---|
| Definition | proviral integration site 3 |
| Date | Results | Publications |
|---|---|---|
| 2019-04-06 10:25:00 | Study found that by promoting the phosphorylation of Stat3 Pim-3 induced the expression of Slug, Snail, and Zeb1, which enhanced epithelial-mesenchymal transition-related changes and induced melanoma migration and invasion. Exploration of the mechanism revealed that Pim-3 bound directly to Stat3 and promoted its phosphorylation. | 29370558 |
| 2013-07-27 11:55:00 | Loss of PIM3 is associated with abnormal hematopoietic phenotypes. | 23360755 |
| 2011-05-21 11:23:00 | investigation of physiological role of Pim3 in beta-cell function: regulates glucose-stimulated insulin secretion; limits ERK signaling; interacts with SOCS6; Pim3 localized to beta-cell; Pim3 knockout mice display increased glucose tolerance | 21099329 |
| 2011-02-26 10:31:00 | Pim-3 has an important role in modulating c-Myc and PGC-1alpha protein levels and cell growth | 21187426 |
| 2010-01-21 00:00:00 | Pim-3 kinase has a novel role in the control of self-renewal of embryonic stem cells. | 17717068 |
| Type | IDs |
|---|---|
| Synonymous | BC026639, Kid1 |
| Gene |
UniProtKB-ID:
PIM3_MOUSE,
Q3TX64_MOUSE
UniprotKB:
P58750,
Q3TX64
UniParc:
UPI0000001A13
EMBL:
AK159600,
AK159670,
BC026639,
AK149478,
BC017621,
AK159399
Ensembl:
ENSMUSG00000035828
KO:
mmu:223775
|
| Nucleutide sequences |
EMBL-CDS:
AAH26639.1,
AAH17621.1,
BAE35274.1,
BAE35220.1,
BAE35052.1,
BAE28905.1
Ensembl_TRS:
ENSMUST00000042818
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000044603
RefSeq:
NP_663453.1
|
| Others |
UniRef100:
UniRef100_P58750
UniRef90:
UniRef90_Q86V86
UniRef50:
UniRef50_Q86V86
UniGene:
Mm.400129,
Mm.474725
CCDS:
CCDS27734.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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