| Type | Description |
|---|---|
| Definition | bromodomain containing 1 |
| Date | Results | Publications |
|---|---|---|
| 2018-03-31 10:36:00 | Brd1(+/-) mice exhibit relational encoding deficits, compromised working and long term memory, as well as impaired executive cognitive functioning with cognitive behaviors relying on medial prefrontal cortex being particularly affected. Akin to patients with schizophrenia, the cognitive deficits displayed by Brd1(+/)(-) mice are not global, but selective. | 28341151 |
| 2018-03-10 11:20:00 | results demonstrate widespread gene expression alterations in the brains of Brd1 +/- mice. | 27837920 |
| 2017-05-20 11:57:00 | BRPF2-MOZ complexes play an important role in the differentiation of embryonic stem cells via H3K14 acetylation. | 27256846 |
| 2015-10-03 10:56:00 | Brd1-mediated Hbo1 activity is crucial for efficient activation of CD8 expression via acetylation at H3K14, which serves as an epigenetic mark that promotes the recruitment of transcription machinery to the CD8 enhancers. | 25519988 |
| 2011-11-19 10:28:00 | The Hbo1-Brd1 complex is the major H3K14 HAT required for transcriptional activation of erythroid developmental regulator genes. | 21753189 |
| Type | IDs |
|---|---|
| Synonymous | 1110059H06Rik, AI316859, mKIAA4191 |
| Gene |
UniProtKB-ID:
BRD1_MOUSE,
Q3UE68_MOUSE,
A7MCW6_MOUSE
UniprotKB:
G5E8P1,
Q3UE68,
A7MCW6
UniParc:
UPI00015C00D6,
UPI0000607606,
UPI0000021EC3,
UPI00005AC8ED
EMBL:
AC158976,
AK086982,
BC152356,
AK149714,
AC117700,
AK220233
Ensembl:
ENSMUSG00000022387
KO:
mmu:223770
|
| Nucleutide sequences |
EMBL-CDS:
BAC39779.1,
BAD90158.1,
BAE29043.1,
AAI52357.1
Ensembl_TRS:
ENSMUST00000109381,
ENSMUST00000109380
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000105006,
ENSMUSP00000105007
RefSeq:
XP_030104370.1,
XP_006520897.1,
XP_006520899.1,
XP_036015261.1,
NP_001028446.2,
XP_006520898.1
|
| Others |
UniRef100:
UniRef100_Q3UE68,
UniRef100_A7MCW6,
UniRef100_G5E8P1
UniRef90:
UniRef90_Q3UE68,
UniRef90_A0A2R8ZY10,
UniRef90_G5E8P1
UniRef50:
UniRef50_A0A2R8ZY10,
UniRef50_G5E8P1,
UniRef50_Q3UE68
UniGene:
Mm.254438
CCDS:
CCDS27730.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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