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22363 Vpreb2

22363

Vpreb2

pre-B lymphocyte gene 2

protein-coding

Mus musculus

基因描述

Type Description
Definition pre-B lymphocyte gene 2

研究结论

Date Results Publications
2015-11-21 11:33:00 Data show no autoantibody production was detectable in surrogate light chain (SLC) components VpreB/CD179a and lambda5/CD179b transgenic mice. 25523463
2012-08-18 10:43:00 VpreB probes the fitness of newly generated VH domains of IgH chains for later pairing with IgL chains, and its non-Ig part fixes the preBCRs on the surface. 22566564
2010-01-21 00:00:00 Data demonstrate that the pre-B-cell receptor is essential for monoallelic silencing of VpreB and lambda5 at the large pre-BII-cell stage. 16281060
2010-01-21 00:00:00 Mice triply deficient for VpreB2 show B cell developmental defects but functional allelic exclusion of the IgH locus. 12055243
2010-01-21 00:00:00 Efficient binding of a soluble murine pre-B cell receptor to stroma cells requires the non-immunoglobulin-like unique tail of lambda 5. 12928380

名称对应

Type IDs
Synonymous CD179b, VpreB1, Vpreb-2
Gene
UniProtKB-ID: VPRE2_MOUSE
UniprotKB: P13373
UniParc: UPI0000021235
EMBL: X05563
Ensembl: ENSMUSG00000059280
KO: mmu:22363
Nucleutide sequences
EMBL-CDS: CAA29077.1
Ensembl_TRS: ENSMUST00000075371
Protein sequencees
Ensembl_PRO: ENSMUSP00000074835
RefSeq: XP_017172433.1, XP_017172434.1, NP_058679.1
Others
UniRef100: UniRef100_P13373
UniRef90: UniRef90_P13372
UniRef50: UniRef50_P13372
UniGene: Mm.377118
CCDS: CCDS28015.1

全选

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