| Type | Description |
|---|---|
| Definition | pre-B lymphocyte gene 1 |
| Date | Results | Publications |
|---|---|---|
| 2015-11-21 11:33:00 | Data show no autoantibody production was detectable in surrogate light chain (SLC) components VpreB/CD179a and lambda5/CD179b transgenic mice. | 25523463 |
| 2012-08-18 10:43:00 | VpreB probes the fitness of newly generated VH domains of IgH chains for later pairing with IgL chains, and its non-Ig part fixes the preBCRs on the surface. | 22566564 |
| 2010-01-21 00:00:00 | The epigenetic profile of immunoglobulin light chain (IgL) genes is strongly influenced by pre-B cell receptor signaling and by the differentiative stage of the progenitor lymphocytes. | 19155482 |
| 2010-01-21 00:00:00 | To identify the sequences that regulate lambda5 and VpreB1 expression during B cell development, the DNaseI hypersensitive sites in the lambda5-VpreB1 functional domain were mapped. | 15950724 |
| 2010-01-21 00:00:00 | Mice triply deficient for VpreB1 show B cell developmental defects but functional allelic exclusion of the IgH locus. | 12055243 |
| Type | IDs |
|---|---|
| Synonymous | CD179a, Vpreb-1 |
| Gene |
UniProtKB-ID:
VPREB_MOUSE,
Q545E0_MOUSE
UniprotKB:
P13372,
Q545E0
UniParc:
UPI0000003EE4
EMBL:
AK010843,
BC117051,
X05557,
AK010879,
X05556
Ensembl:
ENSMUSG00000059305
KO:
mmu:22362
|
| Nucleutide sequences |
EMBL-CDS:
CAA29071.1,
CAA29072.1,
BAB27242.1,
BAB27218.1,
AAI17052.1
Ensembl_TRS:
ENSMUST00000075017
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000074537
RefSeq:
NP_058678.1
|
| Others |
UniRef100:
UniRef100_P13372
UniRef90:
UniRef90_P13372
UniRef50:
UniRef50_P13372
UniGene:
Mm.57574
CCDS:
CCDS27989.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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