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22348 Slc32a1

22348

Slc32a1

solute carrier family 32 (GABA vesicular transporter), member 1

protein-coding

Mus musculus

基因描述

Type Description
Definition solute carrier family 32 (GABA vesicular transporter), member 1

研究结论

Date Results Publications
2021-02-06 13:59:00 Characterization of kindled VGAT-Cre mice as a new animal model of temporal lobe epilepsy. 32954490
2019-07-13 12:16:00 the formation of inhibitory and excitatory synapses onto excitatory neurons requires Vgat in interneurons 29431653
2019-06-15 11:47:00 Intense VIAAT immunoreactivity was found largely confined to the distal tubule epithelia, especially distinct in the inner medulla, although the immunoreactivity was discerned more or less in all tubules and glomeruli 30448467
2018-08-18 12:03:00 Study investigated VIAAT expression during development in: 4 different wildtype-strains, 1 transgenic mouse line with congenital deafness and 1 mouse line with cochlear ablation. Results identify an activity-regulated gradient of VIAAT in the superior olivary complex of NRMI mice. Its absence in other mouse strains adds a novel layer of strain-specific features in the auditory system. 29073893
2018-01-27 11:43:00 GABAergic SVs that lacked the vesicular GABA transporter (VGAT) did not show the pH overshoot and acidified further to approximately 6.0. Comparison of luminal pH dynamics in the presence or absence of VGAT showed that VGAT operates as a GABA/H(+) exchanger, which is continuously required to offset GABA leakage 27601664

名称对应

Type IDs
Synonymous R75019, VGAT, Viaat
Gene
UniProtKB-ID: VIAAT_MOUSE, Q49S98_MOUSE
UniprotKB: O35633, Q49S98
UniParc: UPI0000001F65, UPI0000001F66
EMBL: AY578289, AB080232, AJ001598, BC052020, AK163754, AK163661, AK140468
Ensembl: ENSMUSG00000037771
KO: mmu:22348
Nucleutide sequences
EMBL-CDS: AAH52020.1, CAA04864.1, BAC44889.1, BAC44888.1, BAE24402.1, AAT84437.1, BAE37446.1, BAE37482.1
Ensembl_TRS: ENSMUST00000045738
Protein sequencees
Ensembl_PRO: ENSMUSP00000036299
RefSeq: NP_033534.2, XP_030105353.1
Others
UniRef100: UniRef100_O35633
UniRef90: UniRef90_O35633
UniRef50: UniRef50_O35633
UniGene: Mm.143404, Mm.413854
CCDS: CCDS38309.1

全选

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