| Type | Description |
|---|---|
| Definition | von Hippel-Lindau tumor suppressor |
| Date | Results | Publications |
|---|---|---|
| 2021-03-27 14:44:00 | E3 Ubiquitin Ligase Von Hippel-Lindau Protein Promotes Th17 Differentiation. | 32690659 |
| 2020-10-24 13:58:00 | Rb1/Rbl1/Vhl loss induces mouse subretinal angiomatous proliferation and hemangioblastoma. | 31613797 |
| 2020-06-27 11:51:00 | promotes follicular helper T cell differentiation via glycolytic-epigenetic control | 31123085 |
| 2020-04-25 10:41:00 | a novel role for VHL in mediating nephron progenitor differentiation through metabolic regulation, and suggest that VHL is required for normal kidney development. | 31142573 |
| 2019-12-07 11:31:00 | Study results in transgenic mice demonstrate that the type 2B (murine G518A representing human R167Q) VHL mutation may influence vascular changes and hemangioblastoma formation by accelerating the maturation of larger-caliber arteries in addition to maintaining and expanding capillary density, which could, in turn, worsen pathological progression via blood perfusion defects. | 29467323 |
| Type | IDs |
|---|---|
| Synonymous | Vhlh, pVHL |
| Gene |
UniProtKB-ID:
VHL_MOUSE,
Q3TTE7_MOUSE
UniprotKB:
P40338,
Q3TTE7
UniParc:
UPI000000139B
EMBL:
AF513984,
BC052417,
AK171264,
S76748,
AK171604,
U12570,
AK159238,
AK161408
Ensembl:
ENSMUSG00000033933
KO:
mmu:22346
|
| Nucleutide sequences |
EMBL-CDS:
AAH52417.2,
AAA20662.1,
AAB33363.1,
AAM53645.1,
BAE42557.1,
BAE34921.1,
BAE42352.1,
BAE36378.1
Ensembl_TRS:
ENSMUST00000035673
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000039418
RefSeq:
NP_033533.1
|
| Others |
UniRef100:
UniRef100_P40338
UniRef90:
UniRef90_P40338
UniRef50:
UniRef50_P40338
UniGene:
Mm.29407
CCDS:
CCDS20429.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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