| Type | Description |
|---|---|
| Definition | triple functional domain (PTPRF interacting) |
| Date | Results | Publications |
|---|---|---|
| 2021-03-13 13:18:00 | Rho-GEF trio regulates osteoclast differentiation and function by Rac1/Cdc42. | 32898553 |
| 2020-04-25 12:38:00 | distinct roles of Trio GEF domains in neurite outgrowth | 30850274 |
| 2019-10-26 12:30:00 | Cdh2 signaling via Trio assembles adherens junctions to restrict endothelial permeability. | 30463880 |
| 2019-09-21 11:36:00 | To study the underlying mechanism, we investigated the p38 MAPK pathway and found that loss of Trio blocked the cascade transduction of p38 MAPK signaling. In conclusion, we identified Trio as a novel coordinator in regulating root development and clarified its relevant molecular events. | 30268758 |
| 2019-02-16 10:43:00 | Trio induces RhoA activation downstream of Slit2, and support a functional role in ensuring the proper positioning of both guidepost cells and a major axonal tract. | 30177526 |
| Type | IDs |
|---|---|
| Synonymous | 6720464I07Rik, AA408740, Solo |
| Gene |
UniProtKB-ID:
TRIO_MOUSE
UniprotKB:
Q0KL02
UniParc:
UPI0001B04BC0,
UPI0001B04BC1,
UPI0001B04BC2,
UPI000060747F
EMBL:
BC060724,
AB106872,
AC116808,
AC120373,
AC130219,
AC107452,
AK153924,
BC051169
Ensembl:
ENSMUSG00000022263
KO:
mmu:223435
|
| Nucleutide sequences |
EMBL-CDS:
BAF30811.1,
AAH51169.1,
BAE32258.1
Ensembl_TRS:
ENSMUST00000090247
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000087714
RefSeq:
XP_006520117.1,
XP_006520113.1,
XP_036015216.1,
XP_036015215.1,
XP_030104327.1,
NP_001074771.1,
XP_006520114.1,
XP_006520115.1,
XP_006520116.1
|
| Others |
UniRef100:
UniRef100_Q0KL02
UniRef90:
UniRef90_Q0KL02
UniRef50:
UniRef50_O75962
UniGene:
Mm.485422
CCDS:
CCDS49587.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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