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22333 Vdac1

22333

Vdac1

voltage-dependent anion channel 1

protein-coding

Mus musculus

基因描述

Type Description
Definition voltage-dependent anion channel 1

研究结论

Date Results Publications
2021-04-13 10:11:00 Deletion of VDAC1 Hinders Recovery of Mitochondrial and Renal Functions After Acute Kidney Injury. 32290153
2020-07-18 12:17:00 VDAC1 deficient with polyubiquitination (VDAC1 Poly-KR) hampers mitophagy, but VDAC1 deficient with monoubiquitination (VDAC1 K274R) promotes apoptosis by augmenting the mitochondrial calcium uptake. 32047033
2020-03-07 12:29:00 E73 forms a specific binding site for neurosteroids in mVDAC1. Both neurosteroids and cholesterol bind to a pocket centered at E73, but with opposite orientations. There are four additional sterol binding sites in mVDAC1 that are common to neurosteroids and cholesterol. 31176038
2019-08-03 10:20:00 VDAC's role in control of MOM permeability and regulation of mitochondrial respiration and metabolism. 30412693
2019-07-20 12:17:00 The expression of Vdac1 and total ATP level was decreased in the hippocampus of scopolamine-induced amnesic mice. mitochondrial membrane potential, cristae organization, and morphology were disrupted leading to increased generation and reduced SOD and catalase activity. Vdac1 silencing decreased ATP level and mitochondrial membrane potential leading to increase in degenerated neuronal cells in hippocampus. 29916145

名称对应

Type IDs
Synonymous AL033343, Vdac5, mVDAC1, mVDAC5
Gene
UniProtKB-ID: VDAC1_MOUSE
UniprotKB: Q60932
UniParc: UPI00000008A5, UPI0000028A08
EMBL: U30840, BC092257, AK168672, AK169282, AK169354, AK169671, AK169160, AL645589
Ensembl: ENSMUSG00000020402
KO: mmu:22333
Nucleutide sequences
EMBL-CDS: BAE40522.1, BAE41040.1, BAE41103.1, AAH92257.1, BAE40939.1, AAB47777.1, BAE41292.1
Ensembl_TRS: ENSMUST00000102758, ENSMUST00000020673
Protein sequencees
Ensembl_PRO: ENSMUSP00000099819, ENSMUSP00000020673
RefSeq: NP_035824.1, NP_001349622.1
Others
UniRef100: UniRef100_Q60932
UniRef90: UniRef90_Q60932
UniRef50: UniRef50_Q60932
UniGene: Mm.3555, Mm.470023
CCDS: CCDS24671.1

全选

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