| Type | Description |
|---|---|
| Definition | vascular cell adhesion molecule 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-16 15:53:00 | VCAM-1 targeted alpha-particle therapy for early brain metastases. | 31538194 |
| 2020-12-05 12:59:00 | Pemafibrate, a selective PPARalpha modulator, prevents non-alcoholic steatohepatitis development without reducing the hepatic triglyceride content. | 32385406 |
| 2020-04-25 10:10:00 | These results indicate that MRI based assessment of tumor perfusion and VCAM-1 density can inform about the permissibility of the tumor vasculature for T-cell infiltration which may explain some of the observed variance in treatment response for cancer immunotherapies. | 31521051 |
| 2020-03-21 10:52:00 | allergen- and cytokine-induced VCAM-1 expression is and contributes to lung ILC2 accumulation and downstream eosinophilic inflammation, mucus metaplasia, and type 2 inflammatory responses. | 29900561 |
| 2020-02-22 12:41:00 | In vitro experiments demonstrated that Vcam1 is not involved in the adhesion of tumor cells to lymphatic endothelial cells (LECs) but unexpectedly promoted lymphatic permeability by weakening of lymphatic junctions, most likely through a mechanism triggered by interactions with integrin alpha4 which was also induced in tumor associated LECs. In vivo blockade of Vcam1 reduced lymphatic invasion of 4T1 cells. | 31344266 |
| Type | IDs |
|---|---|
| Synonymous | CD106, Vcam-1 |
| Gene |
UniProtKB-ID:
Q3UPN1_MOUSE
UniprotKB:
Q3UPN1
UniParc:
UPI0000022D56
EMBL:
AC108909,
AK143401
Ensembl:
ENSMUSG00000027962
KO:
mmu:22329
|
| Nucleutide sequences |
EMBL-CDS:
BAE25364.1
Ensembl_TRS:
ENSMUST00000029574
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000029574
RefSeq:
NP_035823.3
|
| Others |
UniRef100:
UniRef100_Q3UPN1
UniRef90:
UniRef90_P29533
UniRef50:
UniRef50_P19320
UniGene:
Mm.76649,
Mm.440909
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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