| Type | Description |
|---|---|
| Definition | vav 2 oncogene |
| Date | Results | Publications |
|---|---|---|
| 2020-12-05 13:00:00 | Vav2 pharmaco-mimetic mice reveal the therapeutic value and caveats of the catalytic inactivation of a Rho exchange factor. | 32528129 |
| 2020-11-28 13:17:00 | Vav2 catalysis-dependent pathways contribute to skeletal muscle growth and metabolic homeostasis. | 33199701 |
| 2020-10-24 14:12:00 | VAV2 signaling promotes regenerative proliferation in both cutaneous and head and neck squamous cell carcinoma. | 32963234 |
| 2018-02-10 10:40:00 | reduction of VAV2 in absence of CUX1 was associated with a significant decrease of RAC1 activity in response to epithelial wounding. Our results identify a novel pathway by which CUX1 regulates normal intestinal epithelial cell restitution | 28893557 |
| 2017-12-16 11:34:00 | This inhibitory action of Vav2 shRNA on Hcys-induced podocyte injury was associated with reduction of Rac1 activity and production. These results suggest that elevated Hcys levels activate Vav2 and thereby increase NOX activity leading to duanyu1670 production, which triggers NLRP3 inflammasome activation, podocyte dysfunction and glomerular injury. | 28193546 |
| Type | IDs |
|---|---|
| Synonymous | 2810040F13Rik, AI847175, Vav-2 |
| Gene |
UniProtKB-ID:
VAV2_MOUSE,
Q7TSI6_MOUSE
UniprotKB:
Q60992,
Q7TSI6
UniParc:
UPI00001A3D1E,
UPI0000028A80
EMBL:
BC053060,
LS482433,
AL772282,
U37017,
AL731552
Ensembl:
ENSMUSG00000009621
KO:
mmu:22325
|
| Nucleutide sequences |
EMBL-CDS:
AAC52761.1,
SPT35810.1,
AAH53060.1
Ensembl_TRS:
ENSMUST00000056176,
ENSMUST00000185188
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000062782,
ENSMUSP00000138964
RefSeq:
XP_006497921.1,
XP_006497919.1,
XP_030105330.1,
XP_006497917.1,
NP_033526.1
|
| Others |
UniRef100:
UniRef100_Q7TSI6,
UniRef100_Q60992
UniRef90:
UniRef90_Q60992,
UniRef90_Q7TSI6
UniRef50:
UniRef50_Q60992,
UniRef50_A0A2U9CEI3
UniGene:
Mm.179011
CCDS:
CCDS15827.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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