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22278 Usf1

22278

Usf1

upstream transcription factor 1

protein-coding

Mus musculus

基因描述

Type Description
Definition upstream transcription factor 1

研究结论

Date Results Publications
2019-12-21 10:05:00 Data suggest that the that the upstream transcription factor 1 (USF1) is indispensable for the proper maintenance of mammalian spermatogenesis. 30759202
2019-09-07 10:58:00 The authors found that USF1 induced miR-125a-3p levels which suppressed Chi3L1 expression. Their results suggest that lung metastasis is suppressed by knock-down of Chi3L1 through miR-125a-3p-mediated up-regulation of USF1. 30214629
2019-02-09 12:05:00 ILEI contributes to melanoma cell invasiveness in vivo without affecting primary tumor growth and is transcriptionally up-regulated by USF-1. 29871931
2019-02-02 12:10:00 Our findings identify USF1 as a novel factor regulating HDL functionality, showing that USF1 inactivation boosts cholesterol efflux, reduces macrophage inflammation and attenuates macrophage cholesterol accumulation, linking improved macrophage cholesterol metabolism and inflammatory pathways to the antiatherogenic function of USF1 deficiency. 30545366
2016-10-29 11:17:00 Mice lacking Usf1 displayed increased BAT-facilitated, diet-induced thermogenesis with up-regulation of mitochondrial respiratory chain complexes, as well as increased BAT activity even at thermoneutrality and after BAT sympathectomy 26819196

名称对应

Type IDs
Synonymous bHLHb11
Gene
UniProtKB-ID: USF1_MOUSE, Q3UQH7_MOUSE, Q8R4E5_MOUSE
UniprotKB: Q61069, Q3UQH7, Q8R4E5
UniParc: UPI00000E5D9C, UPI0000027CED
EMBL: AF479773, AK142437, U41741
Ensembl: ENSMUSG00000026641
KO: mmu:22278
Nucleutide sequences
EMBL-CDS: AAC52921.1, BAE25064.1, AAL87134.1
Ensembl_TRS: ENSMUST00000161241, ENSMUST00000167546
Protein sequencees
Ensembl_PRO: ENSMUSP00000128913, ENSMUSP00000125729
RefSeq: NP_033506.1, XP_030108915.1, XP_030108913.1, NP_001292607.1, XP_030108912.1, NP_001292606.1, NP_001292605.1
Others
UniRef100: UniRef100_Q61069
UniRef90: UniRef90_Q61069
UniRef50: UniRef50_P22415
UniGene: Mm.8
CCDS: CCDS15495.1

全选

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