Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

Science     David E Gordon , Joseph Hiatt , Mehdi Bouhaddou , Veronica V Rezelj , Svenja Ulferts , Hannes Braberg , Alexander S Jureka , Kirsten Obernier , Jeffrey Z Guo , Jyoti Batra , Robyn M Kaake , Andrew R Weckstein , Tristan W Owens , Meghna Gupta , Sergei Pourmal , Erron W Titus , Merve Cakir , Margaret Soucheray , Michael McGregor , Zeynep Cakir , Gwendolyn Jang , Matthew J O'Meara , Tia A Tummino , Ziyang Zhang , Helene Foussard , Ajda Rojc , Yuan Zhou , Dmitry Kuchenov , Ruth Hüttenhain , Jiewei Xu , Manon Eckhardt , Danielle L Swaney , Jacqueline M Fabius , Manisha Ummadi , Beril Tutuncuoglu , Ujjwal Rathore , Maya Modak , Paige Haas , Kelsey M Haas , Zun Zar Chi Naing , Ernst H Pulido , Ying Shi , Inigo Barrio-Hernandez , Danish Memon , Eirini Petsalaki , Alistair Dunham , Miguel Correa Marrero , David Burke , Cassandra Koh , Thomas Vallet , Jesus A Silvas , Caleigh M Azumaya , Christian Billesbølle , Axel F Brilot , Melody G Campbell , Amy Diallo , Miles Sasha Dickinson , Devan Diwanji , Nadia Herrera , Nick Hoppe , Huong T Kratochvil , Yanxin Liu , Gregory E Merz , Michelle Moritz , Henry C Nguyen , Carlos Nowotny , Cristina Puchades , Alexandrea N Rizo , Ursula Schulze-Gahmen , Amber M Smith , Ming Sun , Iris D Young , Jianhua Zhao , Daniel Asarnow , Justin Biel , Alisa Bowen , Julian R Braxton , Jen Chen , Cynthia M Chio , Un Seng Chio , Ishan Deshpande , Loan Doan , Bryan Faust , Sebastian Flores , Mingliang Jin , Kate Kim , Victor L Lam , Fei Li , Junrui Li , Yen-Li Li , Yang Li , Xi Liu , Megan Lo , Kyle E Lopez , Arthur A Melo , Frank R Moss , Phuong Nguyen , Joana Paulino , Komal Ishwar Pawar , Jessica K Peters , Thomas H Pospiech , Maliheh Safari , Smriti Sangwan , Kaitlin Schaefer , Paul V Thomas , Aye C Thwin , Raphael Trenker , Eric Tse , Tsz Kin Martin Tsui , Feng Wang , Natalie Whitis , Zanlin Yu , Kaihua Zhang , Yang Zhang , Fengbo Zhou , Daniel Saltzberg , QCRG Structural Biology Consortium , Anthony J Hodder , Amber S Shun-Shion , Daniel M Williams , Kris M White , Romel Rosales , Thomas Kehrer , Lisa Miorin , Elena Moreno , Arvind H Patel , Suzannah Rihn , Mir M Khalid , Albert Vallejo-Gracia , Parinaz Fozouni , Camille R Simoneau , Theodore L Roth , David Wu , Mohd Anisul Karim , Maya Ghoussaini , Ian Dunham , Francesco Berardi , Sebastian Weigang , Maxime Chazal , Jisoo Park , James Logue , Marisa McGrath , Stuart Weston , Robert Haupt , C James Hastie , Matthew Elliott , Fiona Brown , Kerry A Burness , Elaine Reid , Mark Dorward , Clare Johnson , Stuart G Wilkinson , Anna Geyer , Daniel M Giesel , Carla Baillie , Samantha Raggett , Hannah Leech , Rachel Toth , Nicola Goodman , Kathleen C Keough , Abigail L Lind , Zoonomia Consortium , Reyna J Klesh , Kafi R Hemphill , Jared Carlson-Stevermer , Jennifer Oki , Kevin Holden , Travis Maures , Katherine S Pollard , Andrej Sali , David A Agard , Yifan Cheng , James S Fraser , Adam Frost , Natalia Jura , Tanja Kortemme , Aashish Manglik , Daniel R Southworth , Robert M Stroud , Dario R Alessi , Paul Davies , Matthew B Frieman , Trey Ideker , Carmen Abate , Nolwenn Jouvenet , Georg Kochs , Brian Shoichet , Melanie Ott , Massimo Palmarini , Kevan M Shokat , Adolfo García-Sastre , Jeremy A Rassen , Robert Grosse , Oren S Rosenberg , Kliment A Verba , Christopher F Basler , Marco Vignuzzi , Andrew A Peden , Pedro Beltrao , Nevan J Krogan

A reference map of the human binary protein interactome.

Nature     Katja Luck , Dae-Kyum Kim , Luke Lambourne , Kerstin Spirohn , Bridget E Begg , Wenting Bian , Ruth Brignall , Tiziana Cafarelli , Francisco J Campos-Laborie , Benoit Charloteaux , Dongsic Choi , Atina G Coté , Meaghan Daley , Steven Deimling , Alice Desbuleux , Amélie Dricot , Marinella Gebbia , Madeleine F Hardy , Nishka Kishore , Jennifer J Knapp , István A Kovács , Irma Lemmens , Miles W Mee , Joseph C Mellor , Carl Pollis , Carles Pons , Aaron D Richardson , Sadie Schlabach , Bridget Teeking , Anupama Yadav , Mariana Babor , Dawit Balcha , Omer Basha , Christian Bowman-Colin , Suet-Feung Chin , Soon Gang Choi , Claudia Colabella , Georges Coppin , Cassandra D'Amata , David De Ridder , Steffi De Rouck , Miquel Duran-Frigola , Hanane Ennajdaoui , Florian Goebels , Liana Goehring , Anjali Gopal , Ghazal Haddad , Elodie Hatchi , Mohamed Helmy , Yves Jacob , Yoseph Kassa , Serena Landini , Roujia Li , Natascha van Lieshout , Andrew MacWilliams , Dylan Markey , Joseph N Paulson , Sudharshan Rangarajan , John Rasla , Ashyad Rayhan , Thomas Rolland , Adriana San-Miguel , Yun Shen , Dayag Sheykhkarimli , Gloria M Sheynkman , Eyal Simonovsky , Murat Taşan , Alexander Tejeda , Vincent Tropepe , Jean-Claude Twizere , Yang Wang , Robert J Weatheritt , Jochen Weile , Yu Xia , Xinping Yang , Esti Yeger-Lotem , Quan Zhong , Patrick Aloy , Gary D Bader , Javier De Las Rivas , Suzanne Gaudet , Tong Hao , Janusz Rak , Jan Tavernier , David E Hill , Marc Vidal , Frederick P Roth , Michael A Calderwood

Architecture of the human interactome defines protein communities and disease networks.

Nature     Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization.

Nat. Genet.     Dan E Arking , Sara L Pulit , Lia Crotti , Pim van der Harst , Patricia B Munroe , Tamara T Koopmann , Nona Sotoodehnia , Elizabeth J Rossin , Michael Morley , Xinchen Wang , Andrew D Johnson , Alicia Lundby , Daníel F Gudbjartsson , Peter A Noseworthy , Mark Eijgelsheim , Yuki Bradford , Kirill V Tarasov , Marcus Dörr , Martina Müller-Nurasyid , Annukka M Lahtinen , Ilja M Nolte , Albert Vernon Smith , Joshua C Bis , Aaron Isaacs , Stephen J Newhouse , Daniel S Evans , Wendy S Post , Daryl Waggott , Leo-Pekka Lyytikäinen , Andrew A Hicks , Lewin Eisele , David Ellinghaus , Caroline Hayward , Pau Navarro , Sheila Ulivi , Toshiko Tanaka , David J Tester , Stéphanie Chatel , Stefan Gustafsson , Meena Kumari , Richard W Morris , Åsa T Naluai , Sandosh Padmanabhan , Alexander Kluttig , Bernhard Strohmer , Andrie G Panayiotou , Maria Torres , Michael Knoflach , Jaroslav A Hubacek , Kamil Slowikowski , Soumya Raychaudhuri , Runjun D Kumar , Tamara B Harris , Lenore J Launer , Alan R Shuldiner , Alvaro Alonso , Joel S Bader , Georg Ehret , Hailiang Huang , W H Linda Kao , James B Strait , Peter W Macfarlane , Morris Brown , Mark J Caulfield , Nilesh J Samani , Florian Kronenberg , Johann Willeit , CARe Consortium , COGENT Consortium , J Gustav Smith , Karin H Greiser , Henriette Meyer Zu Schwabedissen , Karl Werdan , Massimo Carella , Leopoldo Zelante , Susan R Heckbert , Bruce M Psaty , Jerome I Rotter , Ivana Kolcic , Ozren PolaÅ¡ek , Alan F Wright , Maura Griffin , Mark J Daly , DCCT/EDIC , David O Arnar , Hilma Hólm , Unnur Thorsteinsdottir , eMERGE Consortium , Joshua C Denny , Dan M Roden , Rebecca L Zuvich , Valur Emilsson , Andrew S Plump , Martin G Larson , Christopher J O'Donnell , Xiaoyan Yin , Marco Bobbo , Adamo P D'Adamo , Annamaria Iorio , Gianfranco Sinagra , Angel Carracedo , Steven R Cummings , Michael A Nalls , Antti Jula , Kimmo K Kontula , Annukka Marjamaa , Lasse Oikarinen , Markus Perola , Kimmo Porthan , Raimund Erbel , Per Hoffmann , Karl-Heinz Jöckel , Hagen Kälsch , Markus M Nöthen , HRGEN Consortium , Marcel den Hoed , Ruth J F Loos , Dag S Thelle , Christian Gieger , Thomas Meitinger , Siegfried Perz , Annette Peters , Hanna Prucha , Moritz F Sinner , Melanie Waldenberger , Rudolf A de Boer , Lude Franke , Pieter A van der Vleuten , Britt Maria Beckmann , Eimo Martens , Abdennasser Bardai , Nynke Hofman , Arthur A M Wilde , Elijah R Behr , Chrysoula Dalageorgou , John R Giudicessi , Argelia Medeiros-Domingo , Julien Barc , Florence Kyndt , Vincent Probst , Alice Ghidoni , Roberto Insolia , Robert M Hamilton , Stephen W Scherer , Jeffrey Brandimarto , Kenneth Margulies , Christine E Moravec , Fabiola del Greco M , Christian Fuchsberger , Jeffrey R O'Connell , Wai K Lee , Graham C M Watt , Harry Campbell , Sarah H Wild , Nour E El Mokhtari , Norbert Frey , Folkert W Asselbergs , Irene Mateo Leach , Gerjan Navis , Maarten P van den Berg , Dirk J van Veldhuisen , Manolis Kellis , Bouwe P Krijthe , Oscar H Franco , Albert Hofman , Jan A Kors , André G Uitterlinden , Jacqueline C M Witteman , Lyudmyla Kedenko , Claudia Lamina , Ben A Oostra , Gonçalo R Abecasis , Edward G Lakatta , Antonella Mulas , Marco Orrú , David Schlessinger , Manuela Uda , Marcello R P Markus , Uwe Völker , Harold Snieder , Timothy D Spector , Johan Ärnlöv , Lars Lind , Johan Sundström , Ann-Christine Syvänen , Mika Kivimaki , Mika Kähönen , Nina Mononen , Olli T Raitakari , Jorma S Viikari , Vera Adamkova , Stefan Kiechl , Maria Brion , Andrew N Nicolaides , Bernhard Paulweber , Johannes Haerting , Anna F Dominiczak , Fredrik Nyberg , Peter H Whincup , Aroon D Hingorani , Jean-Jacques Schott , Connie R Bezzina , Erik Ingelsson , Luigi Ferrucci , Paolo Gasparini , James F Wilson , Igor Rudan , Andre Franke , Thomas W Mühleisen , Peter P Pramstaller , Terho J Lehtimäki , Andrew D Paterson , Afshin Parsa , Yongmei Liu , Cornelia M van Duijn , David S Siscovick , Vilmundur Gudnason , Yalda Jamshidi , Veikko Salomaa , Stephan B Felix , Serena Sanna , Marylyn D Ritchie , Bruno H Stricker , Kari Stefansson , Laurie A Boyer , Thomas P Cappola , Jesper V Olsen , Kasper Lage , Peter J Schwartz , Stefan Kääb , Aravinda Chakravarti , Michael J Ackerman , Arne Pfeufer , Paul I W de Bakker , Christopher Newton-Cheh

Genome-wide association analyses suggest NELL1 influences adverse metabolic response to HCTZ in African Americans.

Pharmacogenomics J.     J L Del-Aguila , A L Beitelshees , R M Cooper-Dehoff , A B Chapman , J G Gums , K Bailey , Y Gong , S T Turner , J A Johnson , E Boerwinkle

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.

Nat. Genet.     Marcel den Hoed , Mark Eijgelsheim , Tõnu Esko , Bianca J J M Brundel , David S Peal , David M Evans , Ilja M Nolte , Ayellet V Segrè , Hilma Holm , Robert E Handsaker , Harm-Jan Westra , Toby Johnson , Aaron Isaacs , Jian Yang , Alicia Lundby , Jing Hua Zhao , Young Jin Kim , Min Jin Go , Peter Almgren , Murielle Bochud , Gabrielle Boucher , Marilyn C Cornelis , Daniel Gudbjartsson , David Hadley , Pim van der Harst , Caroline Hayward , Martin den Heijer , Wilmar Igl , Anne U Jackson , Zoltán Kutalik , Jian'an Luan , John P Kemp , Kati Kristiansson , Claes Ladenvall , Mattias Lorentzon , May E Montasser , Omer T Njajou , Paul F O'Reilly , Sandosh Padmanabhan , Beate St Pourcain , Tuomo Rankinen , Perttu Salo , Toshiko Tanaka , Nicholas J Timpson , Veronique Vitart , Lindsay Waite , William Wheeler , Weihua Zhang , Harmen H M Draisma , Mary F Feitosa , Kathleen F Kerr , Penelope A Lind , Evelin Mihailov , N Charlotte Onland-Moret , Ci Song , Michael N Weedon , Weijia Xie , Loic Yengo , Devin Absher , Christine M Albert , Alvaro Alonso , Dan E Arking , Paul I W de Bakker , Beverley Balkau , Cristina Barlassina , Paola Benaglio , Joshua C Bis , Nabila Bouatia-Naji , Søren Brage , Stephen J Chanock , Peter S Chines , Mina Chung , Dawood Darbar , Christian Dina , Marcus Dörr , Paul Elliott , Stephan B Felix , Krista Fischer , Christian Fuchsberger , Eco J C de Geus , Philippe Goyette , Vilmundur Gudnason , Tamara B Harris , Anna-Liisa Hartikainen , Aki S Havulinna , Susan R Heckbert , Andrew A Hicks , Albert Hofman , Suzanne Holewijn , Femke Hoogstra-Berends , Jouke-Jan Hottenga , Majken K Jensen , Asa Johansson , Juhani Junttila , Stefan Kääb , Bart Kanon , Shamika Ketkar , Kay-Tee Khaw , Joshua W Knowles , Angrad S Kooner , Jan A Kors , Meena Kumari , Lili Milani , Päivi Laiho , Edward G Lakatta , Claudia Langenberg , Maarten Leusink , Yongmei Liu , Robert N Luben , Kathryn L Lunetta , Stacey N Lynch , Marcello R P Markus , Pedro Marques-Vidal , Irene Mateo Leach , Wendy L McArdle , Steven A McCarroll , Sarah E Medland , Kathryn A Miller , Grant W Montgomery , Alanna C Morrison , Martina Müller-Nurasyid , Pau Navarro , Mari Nelis , Jeffrey R O'Connell , Christopher J O'Donnell , Ken K Ong , Anne B Newman , Annette Peters , Ozren Polasek , Anneli Pouta , Peter P Pramstaller , Bruce M Psaty , Dabeeru C Rao , Susan M Ring , Elizabeth J Rossin , Diana Rudan , Serena Sanna , Robert A Scott , Jaban S Sehmi , Stephen Sharp , Jordan T Shin , Andrew B Singleton , Albert V Smith , Nicole Soranzo , Tim D Spector , Chip Stewart , Heather M Stringham , Kirill V Tarasov , André G Uitterlinden , Liesbeth Vandenput , Shih-Jen Hwang , John B Whitfield , Cisca Wijmenga , Sarah H Wild , Gonneke Willemsen , James F Wilson , Jacqueline C M Witteman , Andrew Wong , Quenna Wong , Yalda Jamshidi , Paavo Zitting , Jolanda M A Boer , Dorret I Boomsma , Ingrid B Borecki , Cornelia M van Duijn , Ulf Ekelund , Nita G Forouhi , Philippe Froguel , Aroon Hingorani , Erik Ingelsson , Mika Kivimaki , Richard A Kronmal , Diana Kuh , Lars Lind , Nicholas G Martin , Ben A Oostra , Nancy L Pedersen , Thomas Quertermous , Jerome I Rotter , Yvonne T van der Schouw , W M Monique Verschuren , Mark Walker , Demetrius Albanes , David O Arnar , Themistocles L Assimes , Stefania Bandinelli , Michael Boehnke , Rudolf A de Boer , Claude Bouchard , W L Mark Caulfield , John C Chambers , Gary Curhan , Daniele Cusi , Johan Eriksson , Luigi Ferrucci , Wiek H van Gilst , Nicola Glorioso , Jacqueline de Graaf , Leif Groop , Ulf Gyllensten , Wen-Chi Hsueh , Frank B Hu , Heikki V Huikuri , David J Hunter , Carlos Iribarren , Bo Isomaa , Marjo-Riitta Jarvelin , Antti Jula , Mika Kähönen , Lambertus A Kiemeney , Melanie M van der Klauw , Jaspal S Kooner , Peter Kraft , Licia Iacoviello , Terho Lehtimäki , Marja-Liisa L Lokki , Braxton D Mitchell , Gerjan Navis , Markku S Nieminen , Claes Ohlsson , Neil R Poulter , Lu Qi , Olli T Raitakari , Eric B Rimm , John D Rioux , Federica Rizzi , Igor Rudan , Veikko Salomaa , Peter S Sever , Denis C Shields , Alan R Shuldiner , Juha Sinisalo , Alice V Stanton , Ronald P Stolk , David P Strachan , Jean-Claude Tardif , Unnur Thorsteinsdottir , Jaako Tuomilehto , Dirk J van Veldhuisen , Jarmo Virtamo , Jorma Viikari , Peter Vollenweider , Gérard Waeber , Elisabeth Widen , Yoon Shin Cho , Jesper V Olsen , Peter M Visscher , Cristen Willer , Lude Franke , Global BPgen Consortium , CARDIoGRAM Consortium , Jeanette Erdmann , John R Thompson , PR GWAS Consortium , Arne Pfeufer , QRS GWAS Consortium , Nona Sotoodehnia , QT-IGC Consortium , Christopher Newton-Cheh , CHARGE-AF Consortium , Patrick T Ellinor , Bruno H Ch Stricker , Andres Metspalu , Markus Perola , Jacques S Beckmann , George Davey Smith , Kari Stefansson , Nicholas J Wareham , Patricia B Munroe , Ody C M Sibon , David J Milan , Harold Snieder , Nilesh J Samani , Ruth J F Loos

Genome-wide association analysis identifies multiple loci related to resting heart rate.

Hum Mol Genet     Mark Eijgelsheim , Christopher Newton-Cheh , Nona Sotoodehnia , Paul I W de Bakker , Martina Müller , Alanna C Morrison , Albert V Smith , Aaron Isaacs , Serena Sanna , Marcus Dörr , Pau Navarro , Christian Fuchsberger , Ilja M Nolte , Eco J C de Geus , Karol Estrada , Shih-Jen Hwang , Joshua C Bis , Ina-Maria Rückert , Alvaro Alonso , Lenore J Launer , Jouke Jan Hottenga , Fernando Rivadeneira , Peter A Noseworthy , Kenneth M Rice , Siegfried Perz , Dan E Arking , Tim D Spector , Jan A Kors , Yurii S Aulchenko , Kirill V Tarasov , Georg Homuth , Sarah H Wild , Fabio Marroni , Christian Gieger , Carmilla M Licht , Ronald J Prineas , Albert Hofman , Jerome I Rotter , Andrew A Hicks , Florian Ernst , Samer S Najjar , Alan F Wright , Annette Peters , Ervin R Fox , Ben A Oostra , Heyo K Kroemer , David Couper , Henry Völzke , Harry Campbell , Thomas Meitinger , Manuela Uda , Jacqueline C M Witteman , Bruce M Psaty , H-Erich Wichmann , Tamara B Harris , Stefan Kääb , David S Siscovick , Yalda Jamshidi , André G Uitterlinden , Aaron R Folsom , Martin G Larson , James F Wilson , Brenda W Penninx , Harold Snieder , Peter P Pramstaller , Cornelia M van Duijn , Edward G Lakatta , Stephan B Felix , Vilmundur Gudnason , Arne Pfeufer , Susan R Heckbert , Bruno H Ch Stricker , Eric Boerwinkle , Christopher J O'Donnell

Genome-wide pleiotropy of osteoporosis-related phenotypes: the Framingham Study.

J. Bone Miner. Res.     David Karasik , Yi-Hsiang Hsu , Yanhua Zhou , L Adrienne Cupples , Douglas P Kiel , Serkalem Demissie

Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.

Mol. Med.     Jed E Rose , Frédérique M Behm , Tomas Drgon , Catherine Johnson , George R Uhl

Common genetic variation near the phospholamban gene is associated with cardiac repolarisation: meta-analysis of three genome-wide association studies.

PLoS One     Ilja M Nolte , Chris Wallace , Stephen J Newhouse , Daryl Waggott , Jingyuan Fu , Nicole Soranzo , Rhian Gwilliam , Panos Deloukas , Irina Savelieva , Dongling Zheng , Chrysoula Dalageorgou , Martin Farrall , Nilesh J Samani , John Connell , Morris Brown , Anna Dominiczak , Mark Lathrop , Eleftheria Zeggini , Louise V Wain , Wellcome Trust Case Control Consortium , DCCT/EDIC Research Group , Christopher Newton-Cheh , Mark Eijgelsheim , Kenneth Rice , Paul I W de Bakker , QTGEN consortium , Arne Pfeufer , Serena Sanna , Dan E Arking , QTSCD consortium , Folkert W Asselbergs , Tim D Spector , Nicholas D Carter , Steve Jeffery , Martin Tobin , Mark Caulfield , Harold Snieder , Andrew D Paterson , Patricia B Munroe , Yalda Jamshidi