| Type | Description |
|---|---|
| Definition | unc-5 netrin receptor C |
| Date | Results | Publications |
|---|---|---|
| 2017-08-26 12:36:00 | Here, we report that dissociation of UNC5C and polymerized TUBB3, the highly dynamic beta-tubulin isoform in neurons, is essential for netrin-1/UNC5C-promoted axon repulsion. These results not only provide a working model of direct modulation of MTs by guidance cues in growth cone navigation but also help us to understand molecular mechanisms underlying developmental brain disorders associated with TUBB3 mutations. | 28483977 |
| 2016-04-16 10:23:00 | UNC5C expression levels increased from the 4-cell stage to the blastocyst stage in fertilized murine embryos. Repression of UNC5C in the anterior nucleus stage inhibited development to the blastocyst stage. | 26147436 |
| 2015-02-14 13:12:00 | UNC5c expression is enriched in CA3 hippocampal neurons, but UNC5c is not expressed in microglia or perpheral blood mononuclear cells. | 25419706 |
| 2014-12-20 10:35:00 | Unc5C and DCC act downstream of Ctip2 and Satb2 and contribute to corpus callosum formation. | 24739528 |
| 2014-03-08 11:16:00 | unc5c haploinsufficiency results in diminished amphetamine-induced locomotion in male and female mice. This phenotype is identical to that produced by dcc haploinsufficiency and is observed after adolescence. | 23738838 |
| Type | IDs |
|---|---|
| Synonymous | B130051O18Rik, Unc5h3, rcm |
| Gene |
UniProtKB-ID:
UNC5C_MOUSE,
Q3UQ08_MOUSE,
Q3URW2_MOUSE
UniprotKB:
O08747,
Q3UQ08,
Q3URW2
UniParc:
UPI0000022E41,
UPI0000435204,
UPI00005AC035
EMBL:
AK142411,
BC115772,
U72634,
AK031655,
AK141181,
AK142974
Ensembl:
ENSMUSG00000059921
KO:
mmu:22253
|
| Nucleutide sequences |
EMBL-CDS:
BAC27495.1,
AAB54103.1,
BAE25058.1,
BAE25236.1,
AAI15773.1,
BAE24575.1
Ensembl_TRS:
ENSMUST00000075282,
ENSMUST00000106236,
ENSMUST00000142762
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000074758,
ENSMUSP00000118212,
ENSMUSP00000101843
RefSeq:
NP_033498.1,
NP_001280490.1
|
| Others |
UniRef100:
UniRef100_O08747,
UniRef100_Q3URW2,
UniRef100_Q3UQ08
UniRef90:
UniRef90_G1KPC0,
UniRef90_O08747
UniRef50:
UniRef50_O08747
UniGene:
Mm.24430
CCDS:
CCDS17873.1,
CCDS80034.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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