| Type | Description |
|---|---|
| Definition | unc-13 homolog B |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:13:00 | Heterogeneous Presynaptic Distribution of Munc13 Isoforms at Retinal Synapses and Identification of an Unconventional Bipolar Cell Type with Dual Expression of Munc13 Isoforms: A Study Using Munc13-EXFP Knock-in Mice. | 33105896 |
| 2020-03-21 10:43:00 | Here the authors show that that the C1C2BMUNC2C domain bridges membranes through opposite ends of its elongated structure. Mutations in putative membrane-binding sites lead to corresponding disruptive effects on synaptic vesicle docking, priming, and Ca(2+)-triggered neurotransmitter release in mouse neurons. | 30816091 |
| 2020-02-15 13:22:00 | At hippocampal mossy fiber synapses, RIM-BP2 has a substantial impact on neurotransmitter release by promoting vesicle docking/priming and vesicular release probability via stabilization of Munc13-1 at the active zone. | 31535974 |
| 2019-01-05 12:08:00 | Munc13-1 and Munc18-1, but not CAPS-1/2, stabilize primed synaptic vesicles by preventing NSF-dependent de-priming. | 28635948 |
| 2018-12-01 12:10:00 | Data suggest that the Munc13-1/2 heterodimer is an active component of the vesicle docking, priming and release complex. | 28489077 |
| Type | IDs |
|---|---|
| Synonymous | Munc13-1, Munc13-2, Unc13a, Unc13h1, Unc13h2 |
| Gene |
UniProtKB-ID:
UN13B_MOUSE,
A0A140LHX5_MOUSE,
E9Q263_MOUSE
UniprotKB:
Q9Z1N9,
A0A140LHX5,
E9Q263
UniParc:
UPI0000D65F69,
UPI000024F585,
UPI0001CF38A2,
UPI0001F7892C,
UPI000059DF39
EMBL:
BC157967,
AL732504,
AF115848,
BC158025,
AL772176,
AL672276,
AB162894
Ensembl:
ENSMUSG00000028456
KO:
mmu:22249
|
| Nucleutide sequences |
EMBL-CDS:
BAD32690.1,
AAD13619.1,
AAI58026.1,
AAI57968.1
Ensembl_TRS:
ENSMUST00000163653,
ENSMUST00000079978,
ENSMUST00000107952,
ENSMUST00000207708,
ENSMUST00000107953
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000103586,
ENSMUSP00000078894,
ENSMUSP00000128608,
ENSMUSP00000146589,
ENSMUSP00000103587
RefSeq:
NP_067443.2,
XP_017175605.1,
XP_006537858.1,
XP_036019868.1,
XP_006537852.1,
XP_036019863.1,
XP_006537857.1,
NP_001074882.1,
NP_001371035.1,
XP_036019864.1,
XP_006537851.1,
XP_036019862.1,
XP_036019870.1,
XP_036019869.1,
XP_006537849.1,
XP_036019865.1,
XP_006537854.1,
XP_017175604.1,
XP_036019867.1,
XP_006537853.1,
NP_001297687.1,
XP_036019866.1,
XP_036019861.1
|
| Others |
UniRef100:
UniRef100_E9Q263,
UniRef100_A0A140LHX5,
UniRef100_Q9Z1N9
UniRef90:
UniRef90_Q9Z1N9,
UniRef90_A0A140LHX5,
UniRef90_E9Q263
UniRef50:
UniRef50_Q9Z1N9,
UniRef50_A0A287DDS6
UniGene:
Mm.128892
CCDS:
CCDS80089.1,
CCDS38738.1,
CCDS51161.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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