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22234 Ugcg

22234

Ugcg

UDP-glucose ceramide glucosyltransferase

protein-coding

Mus musculus

基因描述

Type Description
Definition UDP-glucose ceramide glucosyltransferase

研究结论

Date Results Publications
2018-09-15 12:21:00 The cell division gene PCNA was significantly overexpressed in SK2(-/-) cells, suggesting a cross regulation between sphingosine kinases and Ceramide glucosyltransferase. 29673590
2016-06-11 11:41:00 we report the development of a novel, orally available glucosylceramide synthase inhibitor (Genz-682452) with pharmacological and safety profiles that have potential for treating Fabry disease. 25938659
2016-01-16 11:57:00 These results suggest that neuronal glucosylceramide synthase expression modulates mediobasal hypothalamus insulin signaling and white adipose tissue function in fasted mice. 26038579
2015-08-08 11:13:00 we measured the expression and activities of Pgp and GCS, UDP-glucose levels, cellular uptake of C12-NBD-ceramide (a fluorescent analogue of ceramide) and ceramide-induced cell death in S and R cells. 25964538
2014-04-12 10:46:00 Data indicate that verexpression of glucosylceramide synthase in myotubes induces glucosylceramide but enhances insulin signaling. 24214972

名称对应

Type IDs
Synonymous AU043821, C80537, Epcs21, GlcT-1, Ugcgl
Gene
UniProtKB-ID: CEGT_MOUSE
UniprotKB: O88693
UniParc: UPI0000022E85
EMBL: AL808112, BC050828, AB012807, D89866, CH466565
Ensembl: ENSMUSG00000028381
KO: mmu:22234
Nucleutide sequences
EMBL-CDS: AAH50828.1, BAA28782.1, BAA33558.1, EDL02214.1
Ensembl_TRS: ENSMUST00000030074
Protein sequencees
Ensembl_PRO: ENSMUSP00000030074
RefSeq: XP_006537848.1, NP_035803.1
Others
UniRef100: UniRef100_O88693
UniRef90: UniRef90_Q9R0E0
UniRef50: UniRef50_Q9R0E0
UniGene: Mm.198803
CCDS: CCDS18219.1

全选

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