| Type | Description |
|---|---|
| Definition | uncoupling protein 3 (mitochondrial, proton carrier) |
| Date | Results | Publications |
|---|---|---|
| 2021-01-09 13:34:00 | UCP3 reciprocally controls CD4+ Th17 and Treg cell differentiation. | 33211703 |
| 2020-04-11 11:27:00 | The authors demonstrated that UCP3 plays a role in energy and lipid homeostasis and in preserving lean tissues by lipotoxicity, in mice that were housed at thermoneutrality. | 31426456 |
| 2019-12-14 12:10:00 | demonstrate a correlation between mitochondrial membrane potential and mitoflash magnitude in skeletal muscle fibers that is independent of UCP3, and a role for UCP3 in the control of pHlash frequency and of proton leak- and Complex I coupled-respiration in skeletal muscle fibers | 30659802 |
| 2018-07-21 11:57:00 | Our findings, focusing on energy balance, provide a mechanistic understanding of the promising effect of early insulin initiation on lipotoxicity. Insulin, by recovering UCP3 activity, alleviated energy surfeit and potentiated AMPK-mediated lipid homeostasis in skeletal muscle cells following exposure to PA and in gastrocnemius of mice fed HFD. | 29039450 |
| 2018-06-23 11:56:00 | Findings indicate that while heat-induced reduction in uncoupling proteins-3 improves mitochondrial efficiency in vitro, this is not translated to in vivo improvement of exercise economy at 1600 m or 4350 m. | 28174343 |
| Type | IDs |
|---|---|
| Synonymous | AI645527, Slc25a9, UCP-3 |
| Gene |
UniProtKB-ID:
UCP3_MOUSE,
B2RTM2_MOUSE
UniprotKB:
P56501,
B2RTM2
UniParc:
UPI00000235A1
EMBL:
AF032902,
AF030164,
AF053352,
BC139431,
AB008216,
BC139430,
AF019883,
AB013132,
AB010742
Ensembl:
ENSMUSG00000032942
KO:
mmu:22229
|
| Nucleutide sequences |
EMBL-CDS:
AAC28328.1,
BAA25697.1,
AAB71543.1,
AAB87084.1,
AAD01892.1,
BAA33502.1,
BAA31989.1,
AAI39431.1,
AAI39432.1
Ensembl_TRS:
ENSMUST00000032958,
ENSMUST00000107059
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000102674,
ENSMUSP00000032958
RefSeq:
NP_033490.1
|
| Others |
UniRef100:
UniRef100_P56501
UniRef90:
UniRef90_P56499
UniRef50:
UniRef50_P55916
UniGene:
Mm.6254
CCDS:
CCDS21497.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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