| Type | Description |
|---|---|
| Definition | farnesyl-diphosphate farnesyltransferase 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-13 17:13:00 | FDFT1 is a key downstream target of the fasting response and may be involved in CRC cell glucose metabolism. | 32313017 |
| 2019-01-05 10:18:00 | We have demonstrated the differential relative expression levels of FDFT1 mRNA and protein in various types of cancer based on TMAs and IHC for protein expression, and qPCR analysis for the illustration of mRNA expression. | 30468409 |
| 2017-02-04 11:51:00 | The results indicate that the ennea-peptide CLSPHSMFC, tetra-peptides SMFC, CKTE, and WHQW can effectively inhibit Squalene Synthase activities (IC50 values equal to 64, 76, 87, and 90 muM, respectively) | 26922723 |
| 2015-11-21 10:57:00 | The minor allele in FDFT1 was associated with advanced fibrosis in the non-steatotic but not in the steatotic subgroup in patients with chronic hepatitis C. | 23870067 |
| 2014-11-29 12:50:00 | Up-regulation of SQS promotes metastasis of lung cancer by enhancing tumor necrosis factor-alpha receptor 1 and nuclear factor-kappaB activation and matrix metallopeptidase 1 expression. | 25152164 |
| Type | IDs |
|---|---|
| Synonymous | DGPT, ERG9, SQS, SQSD, SS |
| Gene |
UniProtKB-ID:
FDFT_HUMAN,
Q6IAX1_HUMAN,
B7Z9R8_HUMAN,
B4DWP0_HUMAN,
A0A1W2PQ47_HUMAN,
B4DND3_HUMAN
UniprotKB:
P37268,
Q6IAX1,
B7Z9R8,
B4DWP0,
A0A1W2PQ47,
B4DND3
UniParc:
UPI0000D4CC11,
UPI0000481328,
UPI000191533F,
UPI0000E21D66,
UPI00003E022C,
UPI000012A5D5,
UPI00017A77D3,
UPI000178DFE6,
UPI00017A7B35
EMBL:
AK296043,
AK057726,
BC009251,
BC029641,
AC069185,
BC003573,
S76822,
L06105,
X69141,
L06070,
AK297868,
AK316033,
AK301617,
AK300059,
AK315993,
CR457033,
AK316351,
BT006704,
CH471157,
AK316531,
AK316182,
AK293545,
AK316534
Ensembl:
ENSG00000079459
KO:
hsa:2222
|
| Nucleutide sequences |
EMBL-CDS:
BAH14364.1,
BAH14905.1,
BAH11529.1,
AAA60582.1,
BAG51957.1,
CAA48896.1,
AAH03573.1,
AAB33404.1,
AAH29641.1,
BAG58807.1,
BAH14722.1,
BAG61868.1,
AAH09251.1,
BAH14902.1,
AAA36645.1,
CAG33314.1,
EAW65628.1,
EAW65629.1,
AAP35350.1,
BAH14404.1,
BAG63102.1,
BAG60195.1,
BAH14553.1
Gene_ORFName:
hCG_17749
Ensembl_TRS:
ENST00000525777,
ENST00000443614,
ENST00000615631,
ENST00000528643,
ENST00000538689,
ENST00000220584,
ENST00000530664,
ENST00000618539,
ENST00000528812,
ENST00000622850,
ENST00000623368,
ENST00000525954
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000480828,
ENSP00000390367,
ENSP00000481481,
ENSP00000220584,
ENSP00000436069,
ENSP00000484122,
ENSP00000432331,
ENSP00000485229,
ENSP00000431649,
ENSP00000444248,
ENSP00000431749,
ENSP00000491537
RefSeq:
NP_001274680.1,
NP_001274677.1,
NP_001274679.1,
NP_001274671.1,
NP_001274678.1,
NP_001274676.1,
NP_001274673.1,
NP_004453.3,
NP_001274672.1,
NP_001274674.1,
NP_001274685.1
|
| Others |
UniRef100:
UniRef100_B4DWP0,
UniRef100_A0A1W2PQ47,
UniRef100_B7Z9R8,
UniRef100_B4DND3,
UniRef100_P37268
UniRef90:
UniRef90_A0A1U7UEF4,
UniRef90_B4DWP0,
UniRef90_A0A1W2PQ47,
UniRef90_P37268
UniRef50:
UniRef50_C3ZSQ2,
UniRef50_Q32KR6,
UniRef50_P37268
UniGene:
Hs.593928
CCDS:
CCDS75696.1,
CCDS5985.1,
CCDS75697.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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