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22201 Uba1

22201

Uba1

ubiquitin-like modifier activating enzyme 1

protein-coding

Mus musculus

基因描述

Type Description
Definition ubiquitin-like modifier activating enzyme 1

研究结论

Date Results Publications
2020-12-12 13:27:00 Inhibition of the Ubiquitin-Activating Enzyme UBA1 Suppresses Diet-Induced Atherosclerosis in Apolipoprotein E-Knockout Mice. 32258175
2014-08-16 11:27:00 Inhibition of ubiquitin-activating enzyme E1 (Ube1) increases the levels of high- molecular weight mouse Htt in relatively unaffected tissues, declining in the nuclear fraction with age. 24948797
2014-06-07 11:26:00 Dysregulation of UBA1 and subsequent ubiquitination pathways led to beta-catenin accumulation in a model of spinal muscular atrophy. 24590288
2013-03-23 11:53:00 These data suggest that Cys-278 can affect Ub charging through a change in the structural conformation of UBA1, not through direct interaction at the UBA1-Ub interface. 23022194
2010-01-21 00:00:00 biochemical and crystallographic characterization of the two half-domains and the crystal structure of the larger, second catalytic cysteine half-domain of mouse ubiquitin-activating enzyme 15774460

名称对应

Type IDs
Synonymous A1S9, Sbx, Ube-1, Ube1x
Gene
UniProtKB-ID: UBA1_MOUSE, A0A1S6GWH5_MOUSE, B9EHN0_MOUSE
UniprotKB: Q02053, A0A1S6GWH5, B9EHN0
UniParc: UPI0000004191, UPI00001F80C3
EMBL: AK143416, AK088057, D10576, AL807240, BC138200, U09051, U09055, BC058630, AK171667, AK088528, BC145984, KY499679, X62580
Ensembl: ENSMUSG00000001924
KO: mmu:22201
Nucleutide sequences
EMBL-CDS: BAC40121.1, BAA01433.1, BAC40405.1, AAI45985.1, AAC52171.1, CAA44465.1, AAC52169.1, BAE25369.1, AAH58630.1, BAE42599.1, AQS27600.1, AAI38201.1
Ensembl_TRS: ENSMUST00000089217, ENSMUST00000001989
Protein sequencees
Ensembl_PRO: ENSMUSP00000086626, ENSMUSP00000001989
RefSeq: NP_033483.2, NP_001129557.1, XP_030107162.1, NP_001263246.1, NP_001263245.1
Others
UniRef100: UniRef100_Q02053
UniRef90: UniRef90_Q02053
UniRef50: UniRef50_P22314
UniGene: Mm.1104
CCDS: CCDS30044.1

全选

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