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221914 GPC2

221914

GPC2

glypican 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition glypican 2

研究结论

Date Results Publications
2019-07-20 13:04:00 Gpc2 is enriched in neurogenic regions of the adult brain. Its expression is increased by physiological stimuli that increase hippocampal neurogenesis and decreased in transgenic models in which neurogenesis is selectively ablated. Changes in neurogenesis also result in changes in Gpc2 protein level in cerebrospinal fluid (CSF). 28440309
2017-09-30 11:12:00 these findings validate GPC2 as a non-mutated neuroblastoma oncoprotein and candidate immunotherapeutic target. 28898695

名称对应

Type IDs
Gene
UniProtKB-ID: GPC2_HUMAN
UniprotKB: Q8N158
UniParc: UPI000005340D
EMBL: CH236956, BC027972, AL834418, AK096281, CH471091
Ensembl: ENSG00000213420
KO: hsa:221914
Nucleutide sequences
EMBL-CDS: AAH27972.1, EAW76578.1, BAC04745.1, EAL23846.1, CAD39080.1
Ensembl_TRS: ENST00000292377
Protein sequencees
Ensembl_PRO: ENSP00000292377
RefSeq: NP_689955.1
Others
UniRef100: UniRef100_Q8N158
UniRef90: UniRef90_Q8N158
UniRef50: UniRef50_P51653
UniGene: Hs.211701
CCDS: CCDS5689.1

全选

研究热度
该基因近6年没有文献发表
热点单位
排名 科研单位 文献
1

National Cancer Institute

2
2

Molecular Genome Analysis, German Cancer Research Center, 69120 Heidelberg, Germany. s.wiemann@dkfz.de

2
3

Department of Genetics and Genomic Biology, The Hospital for Sick Children, Toronto, Ontario, Canada, M5G 1X8. steve@genet.sickkids.on.ca

1
4

Helix Research Institute

1
5

University of British Columbia

1
热点人员
排名 研究人员 文献
1

Marco A Marra

3
2

Sumio Sugano

2
3

Yutaka Suzuki

2
4

Stefan Wiemann

2
5

Wolfgang Huber

2
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