Type | Description |
---|---|
Definition | protein phosphatase 1 regulatory subunit 35 |
Date | Results | Publications |
---|---|---|
2019-09-14 11:55:00 | Authors found that PPP1R35 is enriched at newborn daughter centrioles in S or G2 phase. In the absence of PPP1R35, centriole assembly initiates normally in S phase, but none of the nascent centrioles can form active centrosomes or recruit CEP295, an essential factor for CCC. | 30230954 |
2019-02-09 10:51:00 | Data show that PPP1R35 acts downstream of, and forms a complex with, RTTN, a microcephaly protein required for distal centriole elongation. | 30168418 |
Type | IDs |
---|---|
Synonymous | C7orf47 |
Gene |
UniProtKB-ID:
PPR35_HUMAN
UniprotKB:
Q8TAP8
UniParc:
UPI000006D9DB
EMBL:
CH236956,
CH471091,
BC026269,
AC092849
Ensembl:
ENSG00000160813
KO:
hsa:221908
|
Nucleutide sequences |
EMBL-CDS:
EAL23833.1,
AAH26269.1,
EAW76532.1
Ensembl_TRS:
ENST00000292330
|
Protein sequencees |
Ensembl_PRO:
ENSP00000292330
RefSeq:
XP_011514216.1,
NP_001333867.1,
NP_659467.1
|
Others |
UniRef100:
UniRef100_Q8TAP8
UniRef90:
UniRef90_Q8TAP8
UniRef50:
UniRef50_Q8TAP8
UniGene:
Hs.413359
CCDS:
CCDS5694.1
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
暂无数据
Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
---|---|---|---|
30230954 |
PPP1R35 ensures centriole homeostasis by promoting centriole-to-centrosome conversion. Mol. Biol. Cell Chii Shyang Fong , Kanako Ozaki , Meng-Fu Bryan Tsou |
2018-11-15 | - |
30168418 |
Elife Andrew Michael Sydor , Etienne Coyaud , Cristina Rovelli , Estelle Laurent , Helen Liu , Brian Raught , Vito Mennella |
2018-08-31 | - |
26496610 |
A human interactome in three quantitative dimensions organized by stoichiometries and abundances. Cell Marco Y Hein , Nina C Hubner , Ina Poser , Jürgen Cox , Nagarjuna Nagaraj , Yusuke Toyoda , Igor A Gak , Ina Weisswange , Jörg Mansfeld , Frank Buchholz , Anthony A Hyman , Matthias Mann |
2015-10-22 |
Cep85l,
Rcc1,
Zbtb48,
Bsdc1,
Kifc1,
Ccp110,
Ints4,
Slc6a8,
Cenpi,
Nup107,
Xpo1,
Fbxw11,
Tubg1,
Csnk1d,
Bap1,
Ptpn23,
Tecpr2,
Slain1,
Ankrd28,
Prkaa1,
Espl1,
Gbf1,
Cdc20,
Cenpf,
Trip11,
Mbd5,
Kif22,
Dut,
Srsf1,
Actb,
Spred2,
Akt2,
Mta1,
Tgs1,
Pip4k2c,
Ankfy1,
Apc,
Ar,
Rhoa,
Atp2a2,
Atp5a1,
Atp7a,
Cep131,
Bach1,
Bcl7c,
Bmpr1a,
Brca1,
Bub1,
Bub1b,
C1qbp,
Anxa2,
Calu,
Cbx1,
Cbx4,
Cct2,
Cct3,
Cct4,
Cct7,
Cct8,
Cd2ap,
Cdk1,
Cdc37,
Cdh1,
Chek1,
Cit,
Copa,
Crebbp,
Cry1,
Csk,
Smc3,
Dctn1,
Ddb1,
Cdk2ap1,
Mapre1,
Ect2,
Eef1a1,
Eif3a,
Mark2,
Evpl,
Ewsr1,
Wdr5,
Dclre1b,
Fbl,
Fgfr1,
Flot1,
Flot2,
B4galt1,
Gnb1,
Gspt1,
Hdac6,
Herc2,
Hsf1,
Hsph1,
Elavl1,
Id2,
Cyr61,
Cep250,
Insr,
Eif3e
|
26673895 |
A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning. Elife Koray Kırlı , Samir Karaca , Heinz Jürgen Dehne , Matthias Samwer , Kuan Ting Pan , Christof Lenz , Henning Urlaub , Dirk Görlich |
2015-01-01 |
CHA1,
KRR1,
SRO9,
STE50,
RRP7,
RNQ1,
DCC1,
GBP2,
SAT4,
RVS161,
YCR016W,
PWP2,
SSK22,
SOL2,
PAT1,
YCR087C-A,
OCA4,
MOB2,
EPL1,
BUD27,
FRS2,
LOC1,
YFR016C,
LSB3,
RPL2A,
PHO4,
SAP155,
IRC6,
ENT4,
PRP19,
RIX7,
YLL032C,
FRA1,
ISA1,
SPA2,
PUF3,
RPL8B,
NOC3,
SSL1,
SSK1,
NSE1,
RLP24,
SDO1,
ADE16,
RPL15A,
STU2,
RPS0B,
FRS1,
BMT6,
KIN2,
HRT3,
REX3,
YLR108C,
CFT2,
MSL5,
ACE2,
STM1,
YLR157C-A,
APS1,
CBF5,
SWI6,
SKG3,
HCR1,
PWP1,
NOP56,
BUR2,
GPN3,
DBP9,
GCD7,
SGD1,
STE11,
NMD4,
RPS22B,
ROM2,
STP3,
IKI3,
REH1,
AFG2,
UTP21,
ATG17,
TUS1,
MAG2,
ATG23,
RPS1A,
FPR4,
PDP3,
CDC24,
RBG1,
FUN12,
MTW1,
PRP45,
MAK16,
ECM1,
GPB2,
VPS8,
KIN3,
CDC15,
YAT1,
WHI4
|
21382349 |
Identification of the human testis protein phosphatase 1 interactome. Biochem. Pharmacol. Margarida Fardilha , Sara L C Esteves , LuÃs Korrodi-Gregório , Ana Paula Vintém , Sara C Domingues , Sandra Rebelo , Nick Morrice , Patricia T W Cohen , Odete A B da Cruz e Silva , Edgar F da Cruz e Silva |
2011-11-15 |
RANBP9,
CCT2,
COPS5,
TOPBP1,
C11orf74,
RNF19B,
CSNK1A1,
CTSL,
PPP1R2P3,
SH3RF2,
CNST,
PPP1R18,
VSTM4,
TUBB,
PPP1R32,
TWISTNB,
PPP1R35,
LMTK2,
CYFIP1,
SMG6,
PPP1R13B,
TPRN,
GSTM5,
GSTZ1,
TRA2A,
NRBP1,
HSPA2,
HSPA8,
ANKRD42,
TCTEX1D4,
JAK2,
C9orf50,
TEX36,
C15orf59,
NEK2,
ATP5B,
APIP,
KRCC1,
DACT1,
PPP1CA,
PPP1CC,
PPP1R2,
PPP1R8,
RIF1,
TBC1D19,
KDM4D,
YLPM1,
SDR39U1,
STARD9,
RRM1,
SFRP1,
CSRNP1,
ACTG1,
C1QA,
TNS1,
TP53BP2,
ZNF24,
GLB1L,
TMEM120A,
ENKD1,
SPATC1L,
PPP1R15B,
DYRK4,
SGCE,
ASH2L,
SPOCD1,
NMT2,
MAP4K4
|
21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
19389623 |
Docking motif-guided mapping of the interactome of protein phosphatase-1. Chem. Biol. Annick Hendrickx , Monique Beullens , Hugo Ceulemans , Tom Den Abt , Aleyde Van Eynde , Emilia Nicolaescu , Bart Lesage , Mathieu Bollen |
2009-04-24 |
FARP1,
MPHOSPH10,
CD2BP2,
CENPE,
KDM5B,
LMTK3,
ELFN2,
PPP1R27,
TMEM132D,
WDR81,
PPP1R21,
ZSWIM3,
PPP1R36,
SH3RF2,
SPRED1,
CNST,
DLG2,
DLG3,
PPP1R32,
PPP1R35,
RRP1B,
FKBP15,
RPGRIP1L,
RIMBP2,
ZBTB38,
TRPC4AP,
SACS,
PCDH11X,
GPR12,
PPP1R37,
TRIM42,
UBN1,
TMEM225,
ITPR3,
GRXCR1,
ELFN1,
MAP1B,
MCM7,
MKI67,
MYO1D,
ORC5,
VPS54,
ZFYVE1,
KCNK10,
HYDIN,
SYTL2,
CHCHD3,
PPP1CA,
GPATCH2,
CEP192,
CASC1,
CASC5,
ARFGEF3,
PHRF1,
CAMSAP3,
SLC7A14,
TSKS,
SH2D4A,
PCIF1,
RBM26,
CSMD1,
DDX31,
WNK1,
TSC2,
CSRNP3,
PREX2,
CSRNP2,
ELL,
CCDC8,
ZCCHC9,
CHCHD6,
NIFK,
SPOCD1,
PKMYT1,
TMEM132C,
KIAA0430,
DZIP3,
SFI1,
SPATA2,
PPP1R26,
PPP1CA
|
15489334 |
Genome Res. Daniela S Gerhard , Lukas Wagner , Elise A Feingold , Carolyn M Shenmen , Lynette H Grouse , Greg Schuler , Steven L Klein , Susan Old , Rebekah Rasooly , Peter Good , Mark Guyer , Allison M Peck , Jeffery G Derge , David Lipman , Francis S Collins , Wonhee Jang , Steven Sherry , Mike Feolo , Leonie Misquitta , Eduardo Lee , Kirill Rotmistrovsky , Susan F Greenhut , Carl F Schaefer , Kenneth Buetow , Tom I Bonner , David Haussler , Jim Kent , Mark Kiekhaus , Terry Furey , Michael Brent , Christa Prange , Kirsten Schreiber , Nicole Shapiro , Narayan K Bhat , Ralph F Hopkins , Florence Hsie , Tom Driscoll , M Bento Soares , Tom L Casavant , Todd E Scheetz , Michael J Brown-stein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Yulan Piao , Dawood B Dudekula , Minoru S H Ko , Koichi Kawakami , Yutaka Suzuki , Sumio Sugano , C E Gruber , M R Smith , Blake Simmons , Troy Moore , Richard Waterman , Stephen L Johnson , Yijun Ruan , Chia Lin Wei , S Mathavan , Preethi H Gunaratne , Jiaqian Wu , Angela M Garcia , Stephen W Hulyk , Edwin Fuh , Ye Yuan , Anna Sneed , Carla Kowis , Anne Hodgson , Donna M Muzny , John McPherson , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madari , Alice C Young , Keith D Wetherby , Steven J Granite , Peggy N Kwong , Charles P Brinkley , Russell L Pearson , Gerard G Bouffard , Robert W Blakesly , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Malachi Griffith , Obi L Griffith , Martin I Krzywinski , Nancy Liao , Ryan Morin , Ryan Morrin , Diana Palmquist , Anca S Petrescu , Ursula Skalska , Duane E Smailus , Jeff M Stott , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Robert A Holt , Agnes Baross , Marco A Marra , Sandra Clifton , Kathryn A Makowski , Stephanie Bosak , Joel Malek , MGC Project Team |
2004-10-01 |
Ldlrap1,
Dnajc3,
Rnaset2a,
Btnl1,
Isg15,
Cyp3a41b,
Ly6c2,
Ccl21b,
Eif3j2,
Mup18,
Lrrc19,
Rcc1,
1700047I17Rik2,
Pcsk9,
Adat3,
Tdrd7,
Sco2,
Gpr153,
Pafah2,
Gm44504,
H6pd,
Adprhl2,
Gpn2,
Rusc2,
Stx12,
Ppp1r8,
Smpdl3b,
Fam46b,
Bsdc1,
Slc44a1,
Zfand2a,
Rubcn,
Kifc1,
Pifo,
C030017K20Rik,
Cbarp,
Rpl5,
Micalcl,
Atg14,
Lrrc8c,
Noc4l,
Nsun5,
Psph,
Trrap,
Mapre3,
Ube3c,
Tbc1d14,
Hscb,
Tyw1,
Emilin1,
Rab28,
Pot1a,
Parp11,
Tada3,
Tra2a,
Brk1,
Fbxl14,
Phrf1,
Plekha1,
Gm21975,
Ric8a,
Mob2,
Prkd2,
Ccp110,
Vrk3,
Grwd1,
Nlrp6,
Trim68,
Psip1,
Spred3,
Faap24,
Ints4,
Rrp8,
Unc45a,
Igflr1,
Sf3b3,
D8Ertd738e,
Usb1,
Champ1,
Smim19,
Exoc8,
Gadd45gip1,
Phkb,
Dohh,
Fam192a,
Enkd1,
Taf5l,
Zdhhc7,
Snapc2,
Ak6,
Gpat4,
Dcun1d2,
Ankrd10,
Cog4,
Hinfp,
Lars2,
Xylb,
Imp3,
Cmtm7
|
12690205 |
Human chromosome 7: DNA sequence and biology. Science Stephen W Scherer , Joseph Cheung , Jeffrey R MacDonald , Lucy R Osborne , Kazuhiko Nakabayashi , Jo-Anne Herbrick , Andrew R Carson , Layla Parker-Katiraee , Jennifer Skaug , Razi Khaja , Junjun Zhang , Alexander K Hudek , Martin Li , May Haddad , Gavin E Duggan , Bridget A Fernandez , Emiko Kanematsu , Simone Gentles , Constantine C Christopoulos , Sanaa Choufani , Dorota Kwasnicka , Xiangqun H Zheng , Zhongwu Lai , Deborah Nusskern , Qing Zhang , Zhiping Gu , Fu Lu , Susan Zeesman , Malgorzata J Nowaczyk , Ikuko Teshima , David Chitayat , Cheryl Shuman , Rosanna Weksberg , Elaine H Zackai , Theresa A Grebe , Sarah R Cox , Susan J Kirkpatrick , Nazneen Rahman , Jan M Friedman , Henry H Q Heng , Pier Giuseppe Pelicci , Francesco Lo-Coco , Elena Belloni , Lisa G Shaffer , Barbara Pober , Cynthia C Morton , James F Gusella , Gail A P Bruns , Bruce R Korf , Bradley J Quade , Azra H Ligon , Heather Ferguson , Anne W Higgins , Natalia T Leach , Steven R Herrick , Emmanuelle Lemyre , Chantal G Farra , Hyung-Goo Kim , Anne M Summers , Karen W Gripp , Wendy Roberts , Peter Szatmari , Elizabeth J T Winsor , Karl-Heinz Grzeschik , Ahmed Teebi , Berge A Minassian , Juha Kere , Lluis Armengol , Miguel Angel Pujana , Xavier Estivill , Michael D Wilson , Ben F Koop , Sabrina Tosi , Gudrun E Moore , Andrew P Boright , Eitan Zlotorynski , Batsheva Kerem , Peter M Kroisel , Erwin Petek , David G Oscier , Sarah J Mould , Hartmut Döhner , Konstanze Döhner , Johanna M Rommens , John B Vincent , J Craig Venter , Peter W Li , Richard J Mural , Mark D Adams , Lap-Chee Tsui |
2003-05-02 |
BET1P1,
LOC100129603,
TUBB3P2,
C7orf72,
LOC100131859,
LOC100286906,
HSPA8P8,
LOC100287825,
DNAJB6,
LINC01006,
LOC100506557,
TMEM178B,
ABCF2,
ARPC1B,
ARL4A,
NAMPT,
AKAP9,
AASS,
LOC101927181,
CDK5,
CDK6,
POP7,
RAMP3,
LOC102724434,
BET1,
IKZF1,
SEMA3A,
NOD1,
GPNMB,
SEMA3C,
AGR2,
ARPC1A,
IGF2BP3,
YKT6,
ADCY1,
CFTR,
FGL2,
CPSF4,
FASTK,
COPS6,
KDELR2,
DUS4L,
NUPL2,
HIBADH,
ZNF277,
CHN2,
TP53TG1,
CHRM2,
GLCCI1,
FKBP9,
CBX3,
ZBED6CL,
TSGA13,
GPR146,
MALSU1,
AGAP3,
ADCYAP1R1,
CLK2P1,
C7orf13,
OR9A4,
CPA1,
C7orf34,
TMEM139,
OR2F2,
SSU72P8,
PRSS37,
KLF14,
SSMEM1,
MTPN,
LRGUK,
ASB10,
PRSS58,
MPLKIP,
ASZ1,
CRHR2,
RUNDC3B,
LINC00689,
KCTD7,
C7orf66,
GIMAP8,
CRYGN,
ZNF425,
CYP3A7,
AMZ1,
RBM33,
AGR3,
CYP3A4,
CYP3A5,
CYP51A1,
DGKB,
DDC,
AEBP1,
GALNTL5,
RNF133,
THAP5,
CCDC71L,
GIMAP7,
BHLHA15,
BMPER
|
12477932 |
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U.S.A. Robert L Strausberg , Elise A Feingold , Lynette H Grouse , Jeffery G Derge , Richard D Klausner , Francis S Collins , Lukas Wagner , Carolyn M Shenmen , Gregory D Schuler , Stephen F Altschul , Barry Zeeberg , Kenneth H Buetow , Carl F Schaefer , Narayan K Bhat , Ralph F Hopkins , Heather Jordan , Troy Moore , Steve I Max , Jun Wang , Florence Hsieh , Luda Diatchenko , Kate Marusina , Andrew A Farmer , Gerald M Rubin , Ling Hong , Mark Stapleton , M Bento Soares , Maria F Bonaldo , Tom L Casavant , Todd E Scheetz , Michael J Brownstein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Christa Prange , Sam S Raha , Naomi A Loquellano , Garrick J Peters , Rick D Abramson , Sara J Mullahy , Stephanie A Bosak , Paul J McEwan , Kevin J McKernan , Joel A Malek , Preethi H Gunaratne , Stephen Richards , Kim C Worley , Sarah Hale , Angela M Garcia , Laura J Gay , Stephen W Hulyk , Debbie K Villalon , Donna M Muzny , Erica J Sodergren , Xiuhua Lu , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madan , Alice C Young , Yuriy Shevchenko , Gerard G Bouffard , Robert W Blakesley , Jeffrey W Touchman , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Martin I Krzywinski , Ursula Skalska , Duane E Smailus , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Marco A Marra , Mammalian Gene Collection Program Team |
2002-12-24 | - |
排名 | 科研单位 | 文献 |
---|---|---|
{{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
排名 | 研究人员 | 文献 |
---|---|---|
{{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员