Type | Description |
---|---|
Definition | Sp8 transcription factor |
Date | Results | Publications |
---|---|---|
2016-08-06 10:31:00 | Data suggest expression of transcription factor p8/SP8 is up-regulated in endoplasmic reticulum stress due to lipotoxicity; overexpression of SP8 up-regulates autophagy; autophagy due to lipotoxicity requires SP8; these reactions are mTOR-independent. | 26733200 |
2014-05-17 10:20:00 | Genetic variants on 3q21 and in the Sp8 transcription factor gene (SP8) as susceptibility loci for psychotic disorders. | 23967141 |
2011-08-20 10:10:00 | This study provided that SP8 are associated with Bipolar I in the Han Chinese population | 20386566 |
2010-09-15 22:05:00 | Observational study of gene-disease association. (HuGE Navigator) | 20634891 |
Type | IDs |
---|---|
Synonymous | BTD |
Gene |
UniProtKB-ID:
SP8_HUMAN,
A8K350_HUMAN
UniprotKB:
Q8IXZ3,
A8K350
UniParc:
UPI000020EBBB,
UPI0000415A36,
UPI00001AADF2,
UPI00001AADF3,
UPI00015DA721
EMBL:
AK290465,
BC038669,
AK056857,
AY167047,
AY167048,
CH471073
Ensembl:
ENSG00000164651
KO:
hsa:221833
|
Nucleutide sequences |
EMBL-CDS:
EAW93731.1,
BAB71297.1,
AAO38028.1,
AAO38029.1,
BAF83154.1
Ensembl_TRS:
ENST00000361443,
ENST00000418710
|
Protein sequencees |
Ensembl_PRO:
ENSP00000408792,
ENSP00000354482
RefSeq:
NP_945194.1,
NP_874359.2
|
Others |
UniRef100:
UniRef100_A8K350,
UniRef100_Q8IXZ3
UniRef90:
UniRef90_Q8IXZ3-2,
UniRef90_Q8IXZ3
UniRef50:
UniRef50_Q8IXZ3,
UniRef50_Q8IXZ3-2
UniGene:
Hs.195922
CCDS:
CCDS43555.1,
CCDS5372.1
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
暂无数据
Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
---|---|---|---|
28473536 |
Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science Yimeng Yin , Ekaterina Morgunova , Arttu Jolma , Eevi Kaasinen , Biswajyoti Sahu , Syed Khund-Sayeed , Pratyush K Das , Teemu Kivioja , Kashyap Dave , Fan Zhong , Kazuhiro R Nitta , Minna Taipale , Alexander Popov , Paul A Ginno , Silvia Domcke , Jian Yan , Dirk Schübeler , Charles Vinson , Jussi Taipale |
2017-05-05 | - |
26733200 |
J Biol Chem Sheng-Nan Jia , Cheng Lin , Dian-Fu Chen , An-Qi Li , Li Dai , Li Zhang , Ling-Ling Zhao , Jin-Shu Yang , Fan Yang , Wei-Jun Yang |
2016-02-26 | - |
23535732 |
Nat Genet Rosalind A Eeles , Ali Amin Al Olama , Sara Benlloch , Edward J Saunders , Daniel A Leongamornlert , Malgorzata Tymrakiewicz , Maya Ghoussaini , Craig Luccarini , Joe Dennis , Sarah Jugurnauth-Little , Tokhir Dadaev , David E Neal , Freddie C Hamdy , Jenny L Donovan , Ken Muir , Graham G Giles , Gianluca Severi , Fredrik Wiklund , Henrik Gronberg , Christopher A Haiman , Fredrick Schumacher , Brian E Henderson , Loic Le Marchand , Sara Lindstrom , Peter Kraft , David J Hunter , Susan Gapstur , Stephen J Chanock , Sonja I Berndt , Demetrius Albanes , Gerald Andriole , Johanna Schleutker , Maren Weischer , Federico Canzian , Elio Riboli , Tim J Key , Ruth C Travis , Daniele Campa , Sue A Ingles , Esther M John , Richard B Hayes , Paul D P Pharoah , Nora Pashayan , Kay-Tee Khaw , Janet L Stanford , Elaine A Ostrander , Lisa B Signorello , Stephen N Thibodeau , Dan Schaid , Christiane Maier , Walther Vogel , Adam S Kibel , Cezary Cybulski , Jan Lubinski , Lisa Cannon-Albright , Hermann Brenner , Jong Y Park , Radka Kaneva , Jyotsna Batra , Amanda B Spurdle , Judith A Clements , Manuel R Teixeira , Ed Dicks , Andrew Lee , Alison M Dunning , Caroline Baynes , Don Conroy , Melanie J Maranian , Shahana Ahmed , Koveela Govindasami , Michelle Guy , Rosemary A Wilkinson , Emma J Sawyer , Angela Morgan , David P Dearnaley , Alan Horwich , Robert A Huddart , Vincent S Khoo , Christopher C Parker , Nicholas J Van As , Christopher J Woodhouse , Alan Thompson , Tim Dudderidge , Chris Ogden , Colin S Cooper , Artitaya Lophatananon , Angela Cox , Melissa C Southey , John L Hopper , Dallas R English , Markus Aly , Jan Adolfsson , Jiangfeng Xu , Siqun L Zheng , Meredith Yeager , Rudolf Kaaks , W Ryan Diver , Mia M Gaudet , Mariana C Stern , Roman Corral , Amit D Joshi , Ahva Shahabi , Tiina Wahlfors , Teuvo L J Tammela , Anssi Auvinen , Jarmo Virtamo , Peter Klarskov , Børge G Nordestgaard , M Andreas Røder , Sune F Nielsen , Stig E Bojesen , Afshan Siddiq , Liesel M Fitzgerald , Suzanne Kolb , Erika M Kwon , Danielle M Karyadi , William J Blot , Wei Zheng , Qiuyin Cai , Shannon K McDonnell , Antje E Rinckleb , Bettina Drake , Graham Colditz , Dominika Wokolorczyk , Robert A Stephenson , Craig Teerlink , Heiko Muller , Dietrich Rothenbacher , Thomas A Sellers , Hui-Yi Lin , Chavdar Slavov , Vanio Mitev , Felicity Lose , Srilakshmi Srinivasan , Sofia Maia , Paula Paulo , Ethan Lange , Kathleen A Cooney , Antonis C Antoniou , Daniel Vincent , François Bacot , Daniel C Tessier , COGSâCancer Research UK GWASâELLIPSE (part of GAME-ON) Initiative , Australian Prostate Cancer Bioresource , UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' Section of Oncology , UK ProtecT (Prostate testing for cancer and Treatment) Study Collaborators , PRACTICAL (Prostate Cancer Association Group to Investigate Cancer-Associated Alterations in the Genome) Consortium , Zsofia Kote-Jarai , Douglas F Easton |
2013-04-01 | - |
23967141 |
PLoS ONE Kenji Kondo , Masashi Ikeda , Yusuke Kajio , Takeo Saito , Yoshimi Iwayama , Branko Aleksic , Kazuo Yamada , Tomoko Toyota , Eiji Hattori , Hiroshi Ujike , Toshiya Inada , Hiroshi Kunugi , Tadafumi Kato , Takeo Yoshikawa , Norio Ozaki , Nakao Iwata |
2013-01-01 |
SP8
|
21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
20386566 |
Genome-wide association study of bipolar I disorder in the Han Chinese population. Mol. Psychiatry M T M Lee , C H Chen , C S Lee , C C Chen , M Y Chong , W C Ouyang , N Y Chiu , L J Chuo , C Y Chen , H K L Tan , H Y Lane , T J Chang , C H Lin , S H Jou , Y M Hou , J Feng , T J Lai , C L Tung , T J Chen , C J Chang , F W Lung , C K Chen , I S Shiah , C Y Liu , P R Teng , K H Chen , L J Shen , C S Cheng , T P Chang , C F Li , C H Chou , C Y Chen , K H T Wang , C S J Fann , J Y Wu , Y T Chen , A T A Cheng |
2011-05-01 |
KCTD12,
C15orf32,
SP8,
ANK3,
CACNB2,
ST8SIA2
|
20634891 |
PLoS ONE Astanand Jugessur , Min Shi , HÃ¥kon Kristian Gjessing , Rolv Terje Lie , Allen James Wilcox , Clarice Ring Weinberg , Kaare Christensen , Abee Lowman Boyles , Sandra Daack-Hirsch , Truc Trung Nguyen , Lene Christiansen , Andrew Carl Lidral , Jeffrey Clark Murray |
2010-07-09 | - |
20339536 |
Genome-wide association of lipid-lowering response to statins in combined study populations. PLoS One Mathew J Barber , Lara M Mangravite , Craig L Hyde , Daniel I Chasman , Joshua D Smith , Catherine A McCarty , Xiaohui Li , Russell A Wilke , Mark J Rieder , Paul T Williams , Paul M Ridker , Aurobindo Chatterjee , Jerome I Rotter , Deborah A Nickerson , Matthew Stephens , Ronald M Krauss |
2010-03-22 | - |
20211142 |
An atlas of combinatorial transcriptional regulation in mouse and man. Cell Timothy Ravasi , Harukazu Suzuki , Carlo Vittorio Cannistraci , Shintaro Katayama , Vladimir B Bajic , Kai Tan , Altuna Akalin , Sebastian Schmeier , Mutsumi Kanamori-Katayama , Nicolas Bertin , Piero Carninci , Carsten O Daub , Alistair R R Forrest , Julian Gough , Sean Grimmond , Jung-Hoon Han , Takehiro Hashimoto , Winston Hide , Oliver Hofmann , Atanas Kamburov , Mandeep Kaur , Hideya Kawaji , Atsutaka Kubosaki , Timo Lassmann , Erik van Nimwegen , Cameron Ross MacPherson , Chihiro Ogawa , Aleksandar Radovanovic , Ariel Schwartz , Rohan D Teasdale , Jesper Tegnér , Boris Lenhard , Sarah A Teichmann , Takahiro Arakawa , Noriko Ninomiya , Kayoko Murakami , Michihira Tagami , Shiro Fukuda , Kengo Imamura , Chikatoshi Kai , Ryoko Ishihara , Yayoi Kitazume , Jun Kawai , David A Hume , Trey Ideker , Yoshihide Hayashizaki |
2010-03-05 | - |
16344560 |
Genome Res. Kouichi Kimura , Ai Wakamatsu , Yutaka Suzuki , Toshio Ota , Tetsuo Nishikawa , Riu Yamashita , Jun-ichi Yamamoto , Mitsuo Sekine , Katsuki Tsuritani , Hiroyuki Wakaguri , Shizuko Ishii , Tomoyasu Sugiyama , Kaoru Saito , Yuko Isono , Ryotaro Irie , Norihiro Kushida , Takahiro Yoneyama , Rie Otsuka , Katsuhiro Kanda , Takahide Yokoi , Hiroshi Kondo , Masako Wagatsuma , Katsuji Murakawa , Shinichi Ishida , Tadashi Ishibashi , Asako Takahashi-Fujii , Tomoo Tanase , Keiichi Nagai , Hisashi Kikuchi , Kenta Nakai , Takao Isogai , Sumio Sugano |
2006-01-01 |
Nefm,
MED6,
CDH2,
PDZK1P1,
DDTL,
ABI1,
GNPDA1,
GTF2IP4,
ZSCAN30,
SRA1,
TMEM170B,
HOTAIR,
FAM86JP,
LOC100126784,
C8orf88,
LOC100128006,
RAB28P5,
MYHAS,
CDC42P3,
LOC100128979,
LOC100128993,
KTN1-AS1,
LOC100129083,
LOC100129204,
TOPORS-AS1,
LINC00484,
ZNF37BP,
FAM47E,
MRVI1-AS1,
ZNF737,
LOC100130075,
MAPT-IT1,
MIR124-2HG,
LINC00861,
LOC100130238,
LOC100130357,
PARD6G-AS1,
LOC100130547,
NFYC-AS1,
EFCAB10,
LOC100130798,
SBK3,
LOC100130849,
LOC100130872,
LOC100130880,
LOC100130987,
LOC100131047,
LINC01135,
CKMT2-AS1,
ZBTB20-AS1,
WDR86-AS1,
CCDC183-AS1,
SNAP25-AS1,
NEMP2,
ZNF503-AS2,
MIR181A1HG,
DBIL5P,
HDAC6,
MZF1-AS1,
ARMCX4,
LINC00271,
ZNF717,
LOC100132057,
LOC100132111,
CALML3-AS1,
NDUFA6-AS1,
FRG1HP,
FCGR1CP,
GXYLT1P3,
GOLGA8F,
DCAF13P3,
IPO5P1,
MSC-AS1,
SMIM9,
FAM66A,
CD24,
UXT-AS1,
JHDM1D-AS1,
UBE2Q2P2,
TEN1,
JMJD7,
PLA2G4B,
LINC00930,
PDCD6IP,
HECTD2-AS1,
ZFHX4-AS1,
FAR2P2,
LOC100233156,
PCED1B-AS1,
PIGK,
LOC100270746,
LOC100270804,
LINC00940,
ERVV-2,
MEF2B,
ZNRF2P2,
NFE2L3P2,
LINC00894,
BCDIN3D-AS1
|
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