| Type | Description |
|---|---|
| Definition | TYRO3 protein tyrosine kinase 3 |
| Date | Results | Publications |
|---|---|---|
| 2020-03-28 10:06:00 | Tyro3 is a therapeutic target for primary effusion lymphoma. | 31346082 |
| 2019-05-18 10:54:00 | Axl and Tyro3, but not Mertk, have an important role in platelet activation and thrombus formation | 30541554 |
| 2019-03-30 10:35:00 | Tyro3/Axl/Mertk-deficient mice develop bone marrow edema which is an early pathological marker in rheumatoid arthritis. | 30335822 |
| 2019-03-23 10:56:00 | Loss of the Tyro3 receptor correlates with significantly thinner myelin sheaths in both unchallenged mice and during remyelination, particularly in larger caliber axons. Primary effect of Tyro3 is upon the radial expansion of myelin. The loss of Tyro3 leads to a reduction in the number of myelin lamellae on axons. | 30208252 |
| 2018-07-14 10:21:00 | Disinhibiation of Gas6 binding to Tyro3 due to PGRN reduction results in activation of via PLCgamma, inducing tau phosphorylation at Ser203, mislocalization of tau to dendritic spines, and spine loss. | 29382817 |
| Type | IDs |
|---|---|
| Synonymous | AI323366, Brt, Dtk, Etk-2, Rse, Sky, TK19-2, Tif, etk2/tyro3, tk19-1 |
| Gene |
UniProtKB-ID:
TYRO3_MOUSE
UniprotKB:
P55144
UniParc:
UPI0000022B69,
UPI0000566A41,
UPI00001EF796
EMBL:
U23721,
BC066058,
X78103,
U05683,
U23719,
U18933,
AB000828,
U18342,
BC082325,
U23720,
U23718,
AB000826,
U18343,
AL844896,
AK141198,
AB000827
Ensembl:
ENSMUSG00000027298
KO:
mmu:22174
|
| Nucleutide sequences |
EMBL-CDS:
AAH82325.1,
AAC52216.1,
AAC52148.1,
BAA19192.1,
AAA19237.1,
AAB26942.1,
BAE24581.1,
BAA19193.1,
AAH66058.1,
AAC52217.1,
AAB26943.1,
AAC52215.1,
CAA54995.1,
BAA19191.1
Ensembl_TRS:
ENSMUST00000110783,
ENSMUST00000028763
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000028763,
ENSMUSP00000106410
RefSeq:
NP_001277729.1,
NP_062265.2,
XP_017172636.2,
XP_006499223.1
|
| Others |
UniRef100:
UniRef100_P55144
UniRef90:
UniRef90_P55144
UniRef50:
UniRef50_Q06418
UniGene:
Mm.2901,
Mm.424496
CCDS:
CCDS16611.1,
CCDS71119.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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