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22166 Txn1

22166

Txn1

thioredoxin 1

protein-coding

Mus musculus

基因描述

Type Description
Definition thioredoxin 1

研究结论

Date Results Publications
2021-04-13 10:07:00 Thioredoxin-1 distinctly promotes NF-kappaB target DNA binding and NLRP3 inflammasome activation independently of Txnip. 32096759
2020-09-12 16:02:00 Thioredoxin1 Inactivation Mediates the Impairment of Ischemia-Induced Angiogenesis and Further Injury in Diabetic Myocardium. 31968349
2020-06-06 12:02:00 Thioredoxin-1 promotes reverse cholesterol transport by upregulating ABCA1 expression through induction of nuclear translocation of LXRalpha, and protects liver from steatosis. 31280865
2020-05-30 12:22:00 unlike T cells, B lymphocytes have a surprisingly robust and flexible cellular redox system to sustain thiol-based cellular redox reactions. Deletion of the Trx1 system in B cells leads to a redox rearrangement toward the GSH/Grx1 pathway in order to maintain redox homeostasis and to fuel DNA biosynthesis during B-cell proliferation. 30802940
2020-05-23 11:40:00 Thioredoxin-1 confines T cell alloresponse and pathogenicity in graft-versus-host disease. 31045571

名称对应

Type IDs
Synonymous ADF, AW550880, Trx1, Txn
Gene
UniProtKB-ID: THIO_MOUSE
UniprotKB: P10639
UniParc: UPI0000163891
EMBL: AK007537, D21859, BC010756, AK007790, X77585, BC094415
Ensembl: ENSMUSG00000028367
KO: mmu:22166
Nucleutide sequences
EMBL-CDS: BAA04881.1, AAH94415.1, BAB25256.1, AAH10756.1, CAA54688.1, BAB25096.1
Ensembl_TRS: ENSMUST00000030051
Protein sequencees
Ensembl_PRO: ENSMUSP00000030051
RefSeq: NP_035790.1
Others
UniRef100: UniRef100_P10639
UniRef90: UniRef90_P11232
UniRef50: UniRef50_P11232
UniGene: Mm.260618
CCDS: CCDS18207.1

全选

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