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221656 KDM1B

221656

KDM1B

lysine demethylase 1B

protein-coding

Homo sapiens

基因描述

Type Description
Definition lysine demethylase 1B

研究结论

Date Results Publications
2020-10-24 14:13:00 [Expression and Clinical Significance of MiR-215 and KDM1B in Patients with Diffuse Large Lymphoma]. 33067956
2020-10-24 13:54:00 Reduction in H3K4me patterns due to aberrant expression of methyltransferases and demethylases in renal cell carcinoma: prognostic and therapeutic implications. 31160694
2020-06-27 10:32:00 While LSD1/CoREST forms a nucleosome docking platform at silenced gene promoters, LSD2/NPAC is a multifunctional enzyme complex with flexible linkers, tailored for rapid chromatin modification, in conjunction with the advance of the RNA polymerase on actively transcribed genes. 30970244
2020-04-18 12:37:00 The expression of LSD2 was associated with higher TNM stage and metastasis of the tumor and thus, might serve as a useful marker for Clear cell renal cell carcinoma (ccRCC) progression. 32097694
2019-08-31 12:46:00 our findings provided new insights into the critical and multifaceted roles of KDM1B in the regulation of cell proliferation and apoptosis, and offered a potentially novel target in preventing the progression of pancreatic cancer. 30846414

名称对应

Type IDs
Synonymous AOF1, C6orf193, LSD2
Gene
UniProtKB-ID: KDM1B_HUMAN, H0Y6H0_HUMAN
UniprotKB: Q8NB78, H0Y6H0
UniParc: UPI000023739E, UPI0000DAC97A, UPI000020D5BB, UPI000006EC6F
EMBL: CH471087, CR627410, AL589723, AL031774, AK125318, AK091217, AK091428
Ensembl: ENSG00000165097
KO: hsa:221656
Nucleutide sequences
EMBL-CDS: BAC86124.1, BAC03663.1, EAW55401.1, CAH10499.1, BAC03612.1
Ensembl_TRS: ENST00000297792, ENST00000650836, ENST00000449850
Protein sequencees
Ensembl_PRO: ENSP00000499208, ENSP00000297792, ENSP00000405669
RefSeq: NP_694587.3, XP_016865934.1, XP_016865930.1, XP_005248982.1, XP_011512688.1, XP_016865931.1, XP_005248985.1, XP_011512687.1, XP_016865929.1, XP_016865935.1, XP_016865932.1, NP_001351543.1
Others
UniRef100: UniRef100_Q8NB78, UniRef100_H0Y6H0
UniRef90: UniRef90_Q8NB78
UniRef50: UniRef50_Q8NB78
UniGene: Hs.709336
CCDS: CCDS34343.1

全选

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