| Type | Description |
|---|---|
| Definition | tubby-like protein 3 |
| Date | Results | Publications |
|---|---|---|
| 2020-04-04 11:13:00 | Embryonic-stage, nephron-specific Tulp3 knockout mice developed cystic kidneys, while retaining intact cilia. | 30799239 |
| 2020-04-04 11:13:00 | Tulp3 controls distinct ciliary pathways that positively or negatively regulate cystogenesis depending on the cellular context. | 30799240 |
| 2017-05-13 21:45:00 | loss of Zfp423 alters expression of several genes encoding key cilium components, including increased expression of Tulp3. Tulp3 is a direct binding target of Zfp423 and reducing the overexpression of Tulp3 in Zfp423-deficient cells suppresses Smoothened translocation defects. | 27727273 |
| 2010-10-23 10:18:00 | Tubby-like protein 3 (TULP3) binds to the IFT-A complex | 20889716 |
| 2010-01-21 00:00:00 | This work uncovers a novel role for Tulp3 as a negative regulatory factor in the hedgehog pathway. | 19334287 |
| Type | IDs |
|---|---|
| Synonymous | 2310022L06Rik, AI316887 |
| Gene |
UniProtKB-ID:
TULP3_MOUSE
UniprotKB:
O88413
UniParc:
UPI00000297C1
EMBL:
AF045582,
AB016963,
BC060068
Ensembl:
ENSMUSG00000001521
KO:
mmu:22158
|
| Nucleutide sequences |
EMBL-CDS:
BAA74752.1,
AAH60068.1,
AAC95430.1
Ensembl_TRS:
ENSMUST00000001562
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000001562
RefSeq:
NP_035787.1
|
| Others |
UniRef100:
UniRef100_O88413
UniRef90:
UniRef90_O88413
UniRef50:
UniRef50_O88413
UniGene:
Mm.291783,
Mm.439490
CCDS:
CCDS39647.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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