| Type | Description |
|---|---|
| Definition | tubulin, beta 5 class I |
| Date | Results | Publications |
|---|---|---|
| 2017-12-16 11:47:00 | Study shows that homozygous TUBB5 knockin animals exhibit a severe reduction in brain size and in body weight. These animals do not show any significant impairment in general activity, anxiety, or in the acoustic startle response, however, present with notable defects in motor coordination. | 28130172 |
| 2016-09-03 10:42:00 | This work sheds light on the functional repertoire of Tubb5, reveals that the E401K mutation acts by a complex mechanism, and demonstrates that the cellular pathology driving TUBB5-associated microcephaly is cell death. | 26903504 |
| 2015-05-30 12:14:00 | TUBB5 is essential for neuronal differentiation and dendritic spine formation in vivo, providing insight into the underlying cellular pathology associated with TUBB5 disease states. | 24833723 |
| 2013-06-08 10:45:00 | results provide insight into the functional repertoire of the tubulin gene family, specifically implicating TUBB5 in embryonic neurogenesis and microcephaly | 23246003 |
| 2010-01-21 00:00:00 | Mutant huntingtin disrupts intracellular transport and insulin secretion by interacting with tubulin beta 5. | 19628478 |
| Type | IDs |
|---|---|
| Synonymous | AA408537, AI596182, B130022C14Rik, M(beta)5 |
| Gene |
UniProtKB-ID:
TBB5_MOUSE
UniprotKB:
P99024
UniParc:
UPI0000001229
EMBL:
AK160225,
AK167808,
AK010960,
AK169295,
AK167779,
AK161575,
AK051164,
AK167691,
AK051393,
AK151215,
AK083327,
AK169123,
AK169210,
CR974451,
AK148978,
AK151670,
AK168271,
AK011263,
BC003825,
X04663,
AK165249,
AK146567,
AK167926,
M28732
Ensembl:
ENSMUSG00000001525
KO:
mmu:22154
|
| Nucleutide sequences |
EMBL-CDS:
BAE39835.1,
BAE40982.1,
BAC34623.1,
BAB27504.1,
BAC38866.1,
CAA28369.1,
BAE35700.1,
BAC34541.1,
BAE27265.1,
BAE36471.1,
BAE39931.1,
BAE39811.1,
BAE30210.1,
BAE40217.1,
BAE38103.1,
BAE40903.1,
BAE41051.1,
BAE39738.1,
AAA40510.1,
AAH03825.1,
BAB27292.1,
BAE30596.1,
BAE28709.1
Ensembl_TRS:
ENSMUST00000001566
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000001566
RefSeq:
NP_035785.1
|
| Others |
UniRef100:
UniRef100_P07437
UniRef90:
UniRef90_P07437
UniRef50:
UniRef50_P07437
UniGene:
Mm.273538,
Mm.472638
CCDS:
CCDS28706.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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