Type | Description |
---|---|
Definition | tubulin, beta 2A class IIA |
Date | Results | Publications |
---|---|---|
2020-01-11 12:14:00 | Study shows that loss of Tubb2a or Tubb2b does not impair survival but does lead to relatively mild cortical malformation phenotypes. In contrast, loss of Tuba1a is perinatal lethal and leads to significant forebrain dysmorphology. The ability of the mouse to survive in the absence of some tubulin genes known to cause disease in humans suggests future intervention strategies for these devastating tubulinopathy diseases. | 31386652 |
2012-06-12 11:51:00 | Smad3 was bound to beta2-tubulin in a TGF-beta1/cGMP-dependent manner. | 21868450 |
Type | IDs |
---|---|
Synonymous | M(beta)2, Tubb2 |
Gene |
UniProtKB-ID:
TBB2A_MOUSE
UniprotKB:
Q7TMM9
UniParc:
UPI000000DC98
EMBL:
BC055441,
AK134545
Ensembl:
ENSMUSG00000058672
KO:
mmu:22151
|
Nucleutide sequences |
EMBL-CDS:
AAH55441.1,
BAE22178.1
Ensembl_TRS:
ENSMUST00000056427
|
Protein sequencees |
Ensembl_PRO:
ENSMUSP00000060246
RefSeq:
NP_033476.1
|
Others |
UniRef100:
UniRef100_Q13885
UniRef90:
UniRef90_Q13885
UniRef50:
UniRef50_Q13885
UniGene:
Mm.422827
CCDS:
CCDS26444.1
|
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---|---|---|---|---|---|---|---|---|
Refseq |
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Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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