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22151 Tubb2a

22151

Tubb2a

tubulin, beta 2A class IIA

protein-coding

Mus musculus

基因描述

Type Description
Definition tubulin, beta 2A class IIA

研究结论

Date Results Publications
2020-01-11 12:14:00 Study shows that loss of Tubb2a or Tubb2b does not impair survival but does lead to relatively mild cortical malformation phenotypes. In contrast, loss of Tuba1a is perinatal lethal and leads to significant forebrain dysmorphology. The ability of the mouse to survive in the absence of some tubulin genes known to cause disease in humans suggests future intervention strategies for these devastating tubulinopathy diseases. 31386652
2012-06-12 11:51:00 Smad3 was bound to beta2-tubulin in a TGF-beta1/cGMP-dependent manner. 21868450

名称对应

Type IDs
Synonymous M(beta)2, Tubb2
Gene
UniProtKB-ID: TBB2A_MOUSE
UniprotKB: Q7TMM9
UniParc: UPI000000DC98
EMBL: BC055441, AK134545
Ensembl: ENSMUSG00000058672
KO: mmu:22151
Nucleutide sequences
EMBL-CDS: AAH55441.1, BAE22178.1
Ensembl_TRS: ENSMUST00000056427
Protein sequencees
Ensembl_PRO: ENSMUSP00000060246
RefSeq: NP_033476.1
Others
UniRef100: UniRef100_Q13885
UniRef90: UniRef90_Q13885
UniRef50: UniRef50_Q13885
UniGene: Mm.422827
CCDS: CCDS26444.1

全选

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研究热度

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