Characterization of guanine nucleotide exchange activity of DH domain of human FGD2.

Protein Expr Purif     Junlan Chuan , Shiyu He , Tian Xie , Ganggang Wang , Zhenglin Yang

A reference map of the human binary protein interactome.

Nature     Katja Luck , Dae-Kyum Kim , Luke Lambourne , Kerstin Spirohn , Bridget E Begg , Wenting Bian , Ruth Brignall , Tiziana Cafarelli , Francisco J Campos-Laborie , Benoit Charloteaux , Dongsic Choi , Atina G Coté , Meaghan Daley , Steven Deimling , Alice Desbuleux , Amélie Dricot , Marinella Gebbia , Madeleine F Hardy , Nishka Kishore , Jennifer J Knapp , István A Kovács , Irma Lemmens , Miles W Mee , Joseph C Mellor , Carl Pollis , Carles Pons , Aaron D Richardson , Sadie Schlabach , Bridget Teeking , Anupama Yadav , Mariana Babor , Dawit Balcha , Omer Basha , Christian Bowman-Colin , Suet-Feung Chin , Soon Gang Choi , Claudia Colabella , Georges Coppin , Cassandra D'Amata , David De Ridder , Steffi De Rouck , Miquel Duran-Frigola , Hanane Ennajdaoui , Florian Goebels , Liana Goehring , Anjali Gopal , Ghazal Haddad , Elodie Hatchi , Mohamed Helmy , Yves Jacob , Yoseph Kassa , Serena Landini , Roujia Li , Natascha van Lieshout , Andrew MacWilliams , Dylan Markey , Joseph N Paulson , Sudharshan Rangarajan , John Rasla , Ashyad Rayhan , Thomas Rolland , Adriana San-Miguel , Yun Shen , Dayag Sheykhkarimli , Gloria M Sheynkman , Eyal Simonovsky , Murat Taşan , Alexander Tejeda , Vincent Tropepe , Jean-Claude Twizere , Yang Wang , Robert J Weatheritt , Jochen Weile , Yu Xia , Xinping Yang , Esti Yeger-Lotem , Quan Zhong , Patrick Aloy , Gary D Bader , Javier De Las Rivas , Suzanne Gaudet , Tong Hao , Janusz Rak , Jan Tavernier , David E Hill , Marc Vidal , Frederick P Roth , Michael A Calderwood

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

Nat. Cell Biol.     Paul M Müller , Juliane Rademacher , Richard D Bagshaw , Celina Wortmann , Carolin Barth , Jakobus van Unen , Keziban M Alp , Girolamo Giudice , Rebecca L Eccles , Louise E Heinrich , Patricia Pascual-Vargas , Marta Sanchez-Castro , Lennart Brandenburg , Geraldine Mbamalu , Monika Tucholska , Lisa Spatt , Maciej T Czajkowski , Robert-William Welke , Sunqu Zhang , Vivian Nguyen , Trendelina Rrustemi , Philipp Trnka , Kiara Freitag , Brett Larsen , Oliver Popp , Philipp Mertins , Anne-Claude Gingras , Frederick P Roth , Karen Colwill , Chris Bakal , Olivier Pertz , Tony Pawson , Evangelia Petsalaki , Oliver Rocks

A proteome-scale map of the human interactome network.

Cell     Thomas Rolland , Murat Taşan , Benoit Charloteaux , Samuel J Pevzner , Quan Zhong , Nidhi Sahni , Song Yi , Irma Lemmens , Celia Fontanillo , Roberto Mosca , Atanas Kamburov , Susan D Ghiassian , Xinping Yang , Lila Ghamsari , Dawit Balcha , Bridget E Begg , Pascal Braun , Marc Brehme , Martin P Broly , Anne-Ruxandra Carvunis , Dan Convery-Zupan , Roser Corominas , Jasmin Coulombe-Huntington , Elizabeth Dann , Matija Dreze , Amélie Dricot , Changyu Fan , Eric Franzosa , Fana Gebreab , Bryan J Gutierrez , Madeleine F Hardy , Mike Jin , Shuli Kang , Ruth Kiros , Guan Ning Lin , Katja Luck , Andrew MacWilliams , Jörg Menche , Ryan R Murray , Alexandre Palagi , Matthew M Poulin , Xavier Rambout , John Rasla , Patrick Reichert , Viviana Romero , Elien Ruyssinck , Julie M Sahalie , Annemarie Scholz , Akash A Shah , Amitabh Sharma , Yun Shen , Kerstin Spirohn , Stanley Tam , Alexander O Tejeda , Shelly A Trigg , Jean-Claude Twizere , Kerwin Vega , Jennifer Walsh , Michael E Cusick , Yu Xia , Albert-László Barabási , Lilia M Iakoucheva , Patrick Aloy , Javier De Las Rivas , Jan Tavernier , Michael A Calderwood , David E Hill , Tong Hao , Frederick P Roth , Marc Vidal

Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris.

Nat Commun     Alexander A Navarini , Michael A Simpson , Michael Weale , Jo Knight , Isabelle Carlavan , Pascale Reiniche , David A Burden , Alison Layton , Veronique Bataille , Michael Allen , Robert Pleass , Andrew Pink , Daniel Creamer , John English , Stephanie Munn , Shernaz Walton , Acne Genetic Study Group , Carolyn Willis , Sophie Déret , Johannes J Voegel , Tim Spector , Catherine H Smith , Richard C Trembath , Jonathan N Barker

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.

Brief. Bioinformatics     Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas

FGD2, a CDC42-specific exchange factor expressed by antigen-presenting cells, localizes to early endosomes and active membrane ruffles.

J Biol Chem     Christoph Huber , Annica MÃ¥rtensson , Gary M Bokoch , David Nemazee , Amanda L Gavin

Mutations in FGD4 encoding the Rho GDP/GTP exchange factor FRABIN cause autosomal recessive Charcot-Marie-Tooth type 4H.

Am. J. Hum. Genet.     Valérie Delague , Arnaud Jacquier , Tarik Hamadouche , Yannick Poitelon , Cécile Baudot , Iréne Boccaccio , Eliane Chouery , Malika Chaouch , Nora Kassouri , Rosette Jabbour , Djamel Grid , Andre Mégarbané , Georg Haase , Nicolas Lévy

Large-scale analysis of the human ubiquitin-related proteome.

Proteomics     Masaki Matsumoto , Shigetsugu Hatakeyama , Koji Oyamada , Yoshiya Oda , Toshihide Nishimura , Keiichi I Nakayama

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

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