| Type | Description |
|---|---|
| Definition | Ttk protein kinase |
| Date | Results | Publications |
|---|---|---|
| 2017-05-27 11:32:00 | using in vitro dephosphorylation assays, we demonstrate that Mastl promotes persistent MPS1 phosphorylation by inhibiting PP2A/B55-mediated MPS1 dephosphorylation rather than affecting Cdk1 kinase activity. Our findings establish a key regulatory function of the Greatwall kinase/Mastl - PP2A/B55 pathway in preventing premature SAC silencing | 27631493 |
| 2015-04-25 12:26:00 | In a sensitized p53(+/-) background, Mps1(DK/DK) mice suffered from rapid-onset acute lymphoblastic lymphoma. | 25197064 |
| 2011-07-23 11:08:00 | Mps1 is essential for meiosis I in mouse. Kinetochore localization of Mps1 is required for correct timing of prometaphase, to prevent precocious APC/C activation, for SAC control, correct aurora C (Aurkc) localization and chromosome alignment. | 21558374 |
| Type | IDs |
|---|---|
| Synonymous | AL022661, Esk1, Mps1, PYT, esk |
| Gene |
UniProtKB-ID:
Q3TPW2_MOUSE,
Q8BX21_MOUSE,
Q8BY97_MOUSE
UniprotKB:
Q3TPW2,
Q8BX21,
Q8BY97
UniParc:
UPI00005B2019,
UPI00005AB6DE,
UPI00000EA58C
EMBL:
AK164093,
AK049200,
AC124011,
AK041487
Ensembl:
ENSMUSG00000038379
KO:
mmu:22137
|
| Nucleutide sequences |
EMBL-CDS:
BAE37623.1,
BAC33605.2,
BAC30960.1
Ensembl_TRS:
ENSMUST00000185913
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000139956
RefSeq:
XP_006511123.1,
XP_006511121.1,
NP_001271201.1,
NP_033471.2,
NP_001103735.1
|
| Others |
UniRef100:
UniRef100_Q8BY97,
UniRef100_Q3TPW2,
UniRef100_Q8BX21
UniRef90:
UniRef90_Q8BX21,
UniRef90_P35761
UniRef50:
UniRef50_Q8BX21,
UniRef50_P33981
UniGene:
Mm.1904
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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