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22113 Phlda2

22113

Phlda2

pleckstrin homology like domain, family A, member 2

protein-coding

Mus musculus

基因描述

Type Description
Definition pleckstrin homology like domain, family A, member 2

研究结论

Date Results Publications
2016-05-28 11:12:00 Phlda2 manipulates the placenta's demands for maternal resources, a process that must be tightly regulated by epigenetic marks to ensure optimal foetal growth. 26476147
2015-05-23 11:25:00 data support a direct role for elevated Phlda2 in limiting fetal growth but also suggest that growth restriction only manifests when there is limited placental reserve 25085993
2013-02-16 11:29:00 TSSC3 plays an important role in the differentiation from trophoblast stem cell to trophoblast progenitors and/or labyrinth trophoblasts through the TSSC3/PI3K/AKT/MASH2 signaling pathway. 23071113
2010-12-08 12:59:00 Phlda2 gene is imprinted, with preferential expression from the maternal allele in placenta. It acts as a rheostat for placental growth, with overgrowth after gene deletion and growth retardation after loss of imprinting. 15327781
2010-01-21 12:25:00 A critical role for the imprinted Phlda2 gene in regulating glycogen storage in the eutherian placenta is identified. 19884348

名称对应

Type IDs
Synonymous Ipl, Tssc3
Gene
UniProtKB-ID: PHLA2_MOUSE
UniprotKB: O08969
UniParc: UPI00000211BC
EMBL: Y15443, BC019141, AK131929, AF002708
Ensembl: ENSMUSG00000010760
KO: mmu:22113
Nucleutide sequences
EMBL-CDS: AAB86681.1, BAE20878.1, AAH19141.1, CAA75634.1
Ensembl_TRS: ENSMUST00000010904
Protein sequencees
Ensembl_PRO: ENSMUSP00000010904
RefSeq: NP_033460.1, XP_006508660.1
Others
UniRef100: UniRef100_O08969
UniRef90: UniRef90_O08969
UniRef50: UniRef50_O08969
UniGene: Mm.334344
CCDS: CCDS22042.1

全选

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