| Type | Description |
|---|---|
| Definition | alkB homolog 3, alpha-ketoglutaratedependent dioxygenase |
| Date | Results | Publications |
|---|---|---|
| 2020-10-31 13:14:00 | ALKBH overexpression in head and neck cancer: potential target for novel anticancer therapy. | 31519943 |
| 2020-06-06 13:57:00 | Evidence that RAD51C-ALKBH3 interaction stimulates ALKBH3-mediated repair of methyl-adduct located within 3'-tailed DNA, which serves as a substrate for the RAD51 recombinase. The lack of RAD51C-ALKBH3 interaction affects ALKBH3 function in vitro and in vivo. | 31642493 |
| 2019-11-30 10:54:00 | Data show that the three DNA repair enzymes ALKBH2, ALKBH3, and AlkB are not only able to repair DNA adducts, but also can edit the epigenetic modification and generate the corresponding oxidative derivatives. | 31114894 |
| 2019-10-19 11:30:00 | In vivo study confirms the regulation effects of ALKBH3 on growth of tumor xenograft. The m1A demethylated tRNA is more sensitive to angiogenin (ANG) cleavage, followed by generating tRNA-derived small RNAs (tDRs) around the anticodon regions. | 30541109 |
| 2019-08-17 10:09:00 | The alteration of ALKBH3 expression, an m1A demethylase, regulates the CSF-1 mRNA stability in breast and ovarian cancer cells | 30342176 |
| Type | IDs |
|---|---|
| Synonymous | ABH3, DEPC-1, DEPC1, PCA1, hABH3 |
| Gene |
UniProtKB-ID:
ALKB3_HUMAN
UniprotKB:
Q96Q83
UniParc:
UPI0000039EA0,
UPI000034E5A1
EMBL:
AB042029,
BC067257,
BC103812,
AC087521,
BC015155,
DQ196343,
BC103814,
BC103813,
CH471064
Ensembl:
ENSG00000166199
KO:
hsa:221120
|
| Nucleutide sequences |
EMBL-CDS:
AAI03815.1,
AAI03813.1,
BAB70508.1,
EAW68078.1,
AAH67257.1,
ABA27096.1,
AAI03814.1,
AAH15155.1
Ensembl_TRS:
ENST00000530803,
ENST00000302708
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000302232,
ENSP00000436788
RefSeq:
NP_631917.1
|
| Others |
UniRef100:
UniRef100_Q96Q83
UniRef90:
UniRef90_Q96Q83
UniRef50:
UniRef50_Q96Q83
UniGene:
Hs.720708
CCDS:
CCDS7906.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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