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221078 NSUN6

221078

NSUN6

NOP2/Sun RNA methyltransferase 6

protein-coding

Homo sapiens

基因描述

Type Description
Definition NOP2/Sun RNA methyltransferase 6

研究结论

Date Results Publications
2021-02-06 13:51:00 Sequence- and structure-specific cytosine-5 mRNA methylation by NSUN6. 33330931
2017-11-11 11:38:00 The structures of NSun6, a human tRNA:m5C methyltransferase, in the apo form and in complex with a full-length tRNA substrate. 28531330
2017-05-27 10:45:00 findings suggest that human NSun6 relies on a delicate network for RNA recognition, which involves both the primary sequence and tertiary structure of tRNA substrates. 27703015
2015-11-21 10:27:00 Findings identified NSUN6 as a novel mammalian m5C tRNA methyltransferase and suggest that methylation of tRNAs by NSUN6 occurs during a late step of tRNA biogenesis, after the addition of the CCA tail and export of the tRNA from the nucleus. 26160102
2010-12-05 22:08:00 Observational study of gene-disease association. (HuGE Navigator) 21044367

名称对应

Type IDs
Synonymous 4933414E04Rik, ARL5B-AS1, NOPD1
Gene
UniProtKB-ID: NSUN6_HUMAN
UniprotKB: Q8TEA1
UniParc: UPI0000073CED
EMBL: AL512641, EF445003, BC035778, CH471072, AK074323, AL450384
Ensembl: ENSG00000241058
KO: hsa:221078
Nucleutide sequences
EMBL-CDS: AAH35778.1, BAB85051.1, EAW86191.1, ACA06032.1, ACA06033.1
Ensembl_TRS: ENST00000377304
Protein sequencees
Ensembl_PRO: ENSP00000366519
RefSeq: XP_016871401.1, NP_001338045.1, NP_001338047.1, NP_001338046.1, XP_011517688.1, XP_011517687.1, XP_011517691.1, XP_016871399.1, XP_024303652.1, XP_011517685.1, XP_011517689.1, XP_016871400.1, XP_016871402.1, XP_011517686.1, XP_016871396.1, NP_872349.1, NP_001338044.1
Others
UniRef100: UniRef100_Q8TEA1
UniRef90: UniRef90_Q8TEA1
UniRef50: UniRef50_Q8TEA1
UniGene: Hs.396175
CCDS: CCDS7130.1

全选

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