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220972 MARCH8

220972

MARCH8

membrane associated ring-CH-type finger 8

protein-coding

Homo sapiens

基因描述

Type Description
Definition membrane associated ring-CH-type finger 8

研究结论

Date Results Publications
2021-02-13 13:28:00 MARCH8 inhibits viral infection by two different mechanisms. 32778221
2020-10-10 12:57:00 MicroRNA-199a-5p regulates glioma progression via targeting MARCH8. 31539136
2020-07-11 10:05:00 MHC II ubiquitination by E3 ubiquitin-protein ligase MARCH8 (MARCH8) and CD83 antigen (CD83) plays a critical role in T cell thymic selection [Review]. 31063934
2020-04-25 12:34:00 MARCH8, a RING-finger E3 ligase, catalyzes K63-linked NS2 polyubiquitination in vitro and in HCV-infected cells. MARCH8 is required for infection with HCV, dengue, and Zika viruses and specifically mediates HCV envelopment. 30759391
2018-09-22 11:26:00 Knockdown of MARCH8 inactivated the PI3K and ss-catenin stat3 signaling pathways by changing protein expression levels or the phosphorylation of related proteins and inhibited migration and invasion of MKN-45 and AGS cells. 30138931

名称对应

Type IDs
Synonymous CMIR, MARCH-VIII, MIR, RNF178, c-MIR
Gene
UniProtKB-ID: MARH8_HUMAN, A0A024R7U2_HUMAN
UniprotKB: Q5T0T0, A0A024R7U2
UniParc: UPI0000EE77CA, UPI000013E4A0
EMBL: AL512595, AL445201, BC025394, AK313340, AL731567, CH471160, BC066988
Ensembl: ENSG00000278545, ENSG00000165406
KO: hsa:220972
Nucleutide sequences
EMBL-CDS: AAH25394.1, AAH66988.1, BAG36144.1, EAW86647.1, EAW86648.1, EAW86650.1, EAW86652.1, EAW86651.1, EAW86649.1, EAW86646.1
Gene_ORFName: hCG_18415
Ensembl_TRS: ENST00000453424, ENST00000395769, ENST00000395771, ENST00000319836
Protein sequencees
Ensembl_PRO: ENSP00000379116, ENSP00000411848, ENSP00000379118, ENSP00000317087
RefSeq: XP_005271861.1, XP_011537797.1, NP_001002266.1, XP_011537794.1, XP_006717767.1, NP_001269795.1, NP_659458.2
Others
UniRef100: UniRef100_Q5T0T0
UniRef90: UniRef90_Q5T0T0
UniRef50: UniRef50_Q6NZQ8-2
UniGene: Hs.499489
CCDS: CCDS60519.1, CCDS7213.1

全选

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