| Type | Description |
|---|---|
| Definition | transducer of ErbB-2.1 |
| Date | Results | Publications |
|---|---|---|
| 2019-04-27 10:23:00 | Our findings provide important insights into a previously unrecognized oncogenic role of Tob1 in colon cancer and suggest that Tob1 is an adverse prognostic factor and therapeutic target for colon cancer. | 30447686 |
| 2018-05-05 10:48:00 | Immune cell-specific transcriptional profiling highlights distinct molecular pathways controlled by Tob1 upon experimental autoimmune encephalomyelitis. | 27546286 |
| 2016-05-14 12:35:00 | MiR-26a exerts its effect by directly targeting Tob1, the negative regulator of BMP/Smad signaling pathway by binding to the 3'-untranslated region and thus repressing Tob1 protein expression | 26050992 |
| 2016-05-14 12:35:00 | Collectively, our data support a model of CNOT7, TOB1, CNOT1, and RNA-binding proteins collectively exerting post-transcriptional control on a metastasis suppressive transcriptional program to drive tumor cell metastasis | 26807845 |
| 2015-10-24 10:04:00 | Nfatc2 and Tob1 have non-overlapping function in T cell negative regulation and tumorigenesis. | 24945807 |
| Type | IDs |
|---|---|
| Synonymous | Tob, Trob |
| Gene |
UniProtKB-ID:
TOB1_MOUSE
UniprotKB:
Q61471
UniParc:
UPI0000025270
EMBL:
D78382,
BC082588,
AL645846
Ensembl:
ENSMUSG00000037573
KO:
mmu:22057
|
| Nucleutide sequences |
EMBL-CDS:
AAH82588.1,
BAA11384.1
Ensembl_TRS:
ENSMUST00000041589
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000036039
RefSeq:
XP_030101781.1,
NP_033453.2
|
| Others |
UniRef100:
UniRef100_Q61471
UniRef90:
UniRef90_Q61471
UniRef50:
UniRef50_Q61471
UniGene:
Mm.259673
CCDS:
CCDS25250.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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