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22045 Trhr

22045

Trhr

thyrotropin releasing hormone receptor

protein-coding

Mus musculus

基因描述

Type Description
Definition thyrotropin releasing hormone receptor

研究结论

Date Results Publications
2015-03-28 13:13:00 activating TRH/TRH-R1 signaling seems not to be sufficient for gastric stimulation of acylated ghrelin production 25490146
2014-01-25 10:42:00 The central nervous systems effects of taltirelin are mediated primarily by TRH-R1 and not TRH-R2. 23303050
2012-10-20 11:47:00 We suggest that persistent signaling by TRHRs is exhibited when sufficient levels of agonist/receptor/G-protein complexes are established and maintained and that TRH-R2 forms and maintains these complexes more efficiently than TRH-R1. 22593547
2010-01-21 00:00:00 Beta-arrestin has a role in desensitization and internalization but not phosphorylation of the thyrotropin-releasing hormone receptor, which causes translocation of endogenous GRK2 to the plasma membrane 16183993
2010-01-21 00:00:00 TRH-R1 has a role in mouse lactation and mice lacking the receptor show signs of central hypothyroidism 14988432

名称对应

Type IDs
Synonymous TRH-R1
Gene
UniProtKB-ID: TRFR_MOUSE, Q32MS1_MOUSE
UniprotKB: P21761, Q32MS1
UniParc: UPI000002930A
EMBL: M94384, M59811, BC109005, BC128269, BC109006, L48936
Ensembl: ENSMUSG00000038760
KO: mmu:22045
Nucleutide sequences
EMBL-CDS: AAA40480.1, AAA81559.1, AAA40437.1, AAI09007.1, AAI28270.1, AAI09006.1
Ensembl_TRS: ENSMUST00000226626, ENSMUST00000038856, ENSMUST00000110289
Protein sequencees
Ensembl_PRO: ENSMUSP00000154650, ENSMUSP00000036320, ENSMUSP00000105918
RefSeq: NP_038724.1, XP_006520811.1
Others
UniRef100: UniRef100_P21761
UniRef90: UniRef90_P34981
UniRef50: UniRef50_P34981
UniGene: Mm.309350
CCDS: CCDS37068.1

全选

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研究热度

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