| Type | Description |
|---|---|
| Definition | three prime repair exonuclease 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-15 16:03:00 | these findings demonstrate that TREX1 enzymatic activity is crucial to prevent inappropriate DNA sensing and IFN type I production in immune cells | 31826941 |
| 2020-07-18 11:04:00 | These results indicate that cGAS is a key mediator in the autoimmune disease associated with defective TREX1 function, providing additional insights into disease pathogenesis and guidance to the development of therapeutics for human systemic autoimmune disorders. | 30872080 |
| 2019-04-20 10:21:00 | Leu24-Pro25-Ser26 cluster of TREX1 served to cap the nonscissile 5'-end of the DNA for precise removal of the short 3'-overhang in L- and Y-structural DNA or to wedge into the double-stranded region for further digestion along the duplex | 29734329 |
| 2018-11-24 10:48:00 | Trex1 is an upstream regulator of radiation-driven anti-tumor immunity. Trex1 induction may guide the selection of radiation dose and fractionation in patients treated with immunotherapy. | 28598415 |
| 2017-11-25 13:19:00 | the cell-cycle-dependent post-translation modification of TREX1 regulates its interaction with OST. | 28297665 |
| Type | IDs |
|---|---|
| Synonymous | AU041952 |
| Gene |
UniProtKB-ID:
TREX1_MOUSE
UniprotKB:
Q91XB0
UniParc:
UPI000002606F
EMBL:
AK087832,
BC011133,
AF319574,
AK009899,
AK171916,
AF151106
Ensembl:
ENSMUSG00000049734
KO:
mmu:22040
|
| Nucleutide sequences |
EMBL-CDS:
AAK07621.1,
BAB26571.2,
AAH11133.1,
BAE42731.1,
AAD48775.2,
BAC40020.1
Ensembl_TRS:
ENSMUST00000061973,
ENSMUST00000112053
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000050971,
ENSMUSP00000107684
RefSeq:
NP_035767.4,
NP_001012236.1
|
| Others |
UniRef100:
UniRef100_Q91XB0
UniRef90:
UniRef90_Q91XB0
UniRef50:
UniRef50_Q91XB0
UniGene:
Mm.439964
CCDS:
CCDS23544.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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