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2204 FCAR

2204

FCAR

Fc fragment of IgA receptor

protein-coding

Homo sapiens

基因描述

Type Description
Definition Fc fragment of IgA receptor

研究结论

Date Results Publications
2020-10-10 12:58:00 Serum Soluble CD89-IgA Complexes Are Elevated in IgA Nephropathy without Immunosuppressant History. 32076466
2018-04-14 10:33:00 FcalphaRI-induced cytokine production is orchestrated via upregulation of cytokine translation and caspase-1 activation, which is dependent on glycolytic reprogramming. 29491406
2017-07-22 12:47:00 In transgenic mice, IgAN pathogenesis involves impaired clearance of abnormal IgA via CD89, primarily by the Kupffer cells. Conditional IgAN progression in CD89 transgenic mice thus reveals important aspects of IgAN pathogenesis. 27437939
2017-06-24 10:40:00 a novel Fcar splice variant termed variant APD isolated from a healthy volunteer that lacks only the IgA-binding EC1 domain, is reported. 28103138
2015-11-21 10:58:00 Findings suggest a basis for the use of Fc receptor I for IgA (FcalphaRI) as a molecular target for the treatment of lupus. 25907714

名称对应

Type IDs
Synonymous CD89, CTB-61M7.2, FcalphaRI
Gene
UniProtKB-ID: FCAR_HUMAN, A0A024R4R4_HUMAN, A0A024R4N4_HUMAN
UniprotKB: P24071, A0A024R4R4, A0A024R4N4
UniParc: UPI000000037F, UPI000006D973, UPI000002A976, UPI000000037E, UPI000011B429, UPI000006ECE7, UPI000006FEF0, UPI000002A977, UPI0000071920, UPI000002A975, UPI0000070F8E
EMBL: X54150, D87857, X87769, D87853, D87859, X87766, DQ075339, DQ075336, D87855, DQ075335, D87854, AC011501, DQ075338, X87767, D87856, BC027953, S82919, U43774, D87862, DQ075334, U43677, X87768, U56236, DQ075337, CH471135, D87861, X87765, U56237
Ensembl: ENSG00000275136, ENSG00000283750, ENSG00000276858, ENSG00000186431, ENSG00000283953, ENSG00000284061, ENSG00000275269, ENSG00000284004, ENSG00000274580, ENSG00000276985, ENSG00000275564, ENSG00000273738, ENSG00000275970, ENSG00000278415, ENSG00000284245
KO: hsa:2204
Nucleutide sequences
EMBL-CDS: AAB00567.1, BAA13475.1, BAA13474.1, BAA13477.1, BAA13471.1, AAC50595.1, AAD14421.1, CAA61039.1, AAZ76580.1, BAA13472.1, AAZ76577.1, AAZ76582.1, AAB00566.1, AAZ76578.1, AAH27953.1, CAA38089.1, AAC50639.1, BAA13473.1, BAA13479.1, AAZ76579.1, BAA13480.1, AAZ76581.1, EAW72303.1, EAW72301.1
Gene_ORFName: hCG_20262, hCG_20262
Ensembl_TRS: ENST00000622646, ENST00000621702, ENST00000617778, ENST00000611018, ENST00000640462, ENST00000620162, ENST00000615829, ENST00000488066, ENST00000611943, ENST00000469767, ENST00000638244, ENST00000639575, ENST00000620270, ENST00000618985, ENST00000622470, ENST00000638625, ENST00000391723, ENST00000617766, ENST00000640415, ENST00000620822, ENST00000621755, ENST00000615937, ENST00000612803, ENST00000621289, ENST00000618328, ENST00000622777, ENST00000640618, ENST00000391724, ENST00000614689, ENST00000619073, ENST00000621882, ENST00000622883, ENST00000620179, ENST00000616878, ENST00000616340, ENST00000640025, ENST00000391725, ENST00000638453, ENST00000622904, ENST00000614917, ENST00000611130, ENST00000619385, ENST00000353758, ENST00000359272, ENST00000639014, ENST00000614298, ENST00000620801, ENST00000640878, ENST00000639402, ENST00000640582, ENST00000619155, ENST00000639193, ENST00000640405, ENST00000621684, ENST00000640584, ENST00000638206, ENST00000638553, ENST00000617609, ENST00000622157, ENST00000615703, ENST00000639428, ENST00000617762, ENST00000614893, ENST00000638285, ENST00000616969, ENST00000615361, ENST00000640032, ENST00000619414, ENST00000621417, ENST00000613201, ENST00000614954, ENST00000639426, ENST00000617025, ENST00000612159, ENST00000619822, ENST00000639455, ENST00000615719, ENST00000620397, ENST00000611871, ENST00000615110, ENST00000638995, ENST00000622737, ENST00000639763, ENST00000620873, ENST00000617964, ENST00000613663, ENST00000618658, ENST00000621004, ENST00000640239, ENST00000610340, ENST00000612150, ENST00000638212, ENST00000638945, ENST00000640918, ENST00000618287, ENST00000615800, ENST00000640430, ENST00000640811, ENST00000638900, ENST00000610397, ENST00000638966, ENST00000622543, ENST00000614226, ENST00000622491, ENST00000391726, ENST00000639223, ENST00000640063, ENST00000640908, ENST00000639178, ENST00000640047, ENST00000639163, ENST00000618805, ENST00000640687, ENST00000638882, ENST00000615040, ENST00000613318, ENST00000638527, ENST00000612918, ENST00000612815, ENST00000355524, ENST00000613298, ENST00000612505, ENST00000621009, ENST00000617696, ENST00000345937, ENST00000613199, ENST00000640761, ENST00000614433, ENST00000610786, ENST00000613685, ENST00000618271
Protein sequencees
Ensembl_PRO: ENSP00000483099, ENSP00000492529, ENSP00000481366, ENSP00000482025, ENSP00000479880, ENSP00000480965, ENSP00000483472, ENSP00000492321, ENSP00000479924, ENSP00000482807, ENSP00000483121, ENSP00000484136, ENSP00000477643, ENSP00000491307, ENSP00000492699, ENSP00000479360, ENSP00000482334, ENSP00000482022, ENSP00000484868, ENSP00000480748, ENSP00000484141, ENSP00000483402, ENSP00000478454, ENSP00000478315, ENSP00000474512, ENSP00000492442, ENSP00000480461, ENSP00000479831, ENSP00000492274, ENSP00000492077, ENSP00000492447, ENSP00000478634, ENSP00000482108, ENSP00000484662, ENSP00000491493, ENSP00000479230, ENSP00000375603, ENSP00000481560, ENSP00000482623, ENSP00000492226, ENSP00000491778, ENSP00000484741, ENSP00000492755, ENSP00000482056, ENSP00000347714, ENSP00000479792, ENSP00000484906, ENSP00000483437, ENSP00000492137, ENSP00000482670, ENSP00000484816, ENSP00000483327, ENSP00000483503, ENSP00000492162, ENSP00000482976, ENSP00000480323, ENSP00000375604, ENSP00000491362, ENSP00000480496, ENSP00000375606, ENSP00000479099, ENSP00000491556, ENSP00000478233, ENSP00000375605, ENSP00000481985, ENSP00000477610, ENSP00000490997, ENSP00000478163, ENSP00000491372, ENSP00000338058, ENSP00000352218, ENSP00000491595, ENSP00000481668, ENSP00000483250, ENSP00000477656, ENSP00000492678, ENSP00000483841, ENSP00000492762, ENSP00000492494, ENSP00000481230, ENSP00000480444, ENSP00000478465, ENSP00000491274, ENSP00000482741, ENSP00000479738, ENSP00000482273, ENSP00000477673, ENSP00000481676, ENSP00000491849, ENSP00000491039, ENSP00000492749, ENSP00000481129, ENSP00000473814, ENSP00000491447, ENSP00000481195, ENSP00000482518, ENSP00000477966, ENSP00000492411, ENSP00000479039, ENSP00000482451, ENSP00000479239, ENSP00000479688, ENSP00000481394, ENSP00000481502, ENSP00000491746, ENSP00000338257, ENSP00000491741, ENSP00000492686, ENSP00000491889, ENSP00000492228, ENSP00000481345, ENSP00000480013, ENSP00000484917, ENSP00000492230, ENSP00000478075, ENSP00000480406, ENSP00000491490, ENSP00000484483, ENSP00000491818, ENSP00000492597, ENSP00000484272, ENSP00000491642, ENSP00000483258, ENSP00000491298, ENSP00000484276, ENSP00000491420, ENSP00000491815, ENSP00000477584, ENSP00000480498, ENSP00000480970, ENSP00000492415
RefSeq: NP_579803.1, NP_579807.1, NP_579811.1, NP_579812.1, NP_001991.1, NP_579805.1, NP_579808.1, XP_016881962.1, XP_016881963.1, XP_011524927.1, NP_579806.1
Others
UniRef100: UniRef100_A0A024R4N4, UniRef100_P24071, UniRef100_A0A024R4R4
UniRef90: UniRef90_P24071, UniRef90_P24071-6
UniRef50: UniRef50_P24071
UniGene: Hs.659872
CCDS: CCDS12910.1, CCDS42622.1, CCDS12908.1, CCDS12907.1, CCDS42624.1, CCDS42625.1, CCDS42623.1, CCDS12909.1

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