| Type | Description |
|---|---|
| Definition | TNF receptor-associated factor 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-29 12:46:00 | TRAF2 Ser-11 Phosphorylation Promotes Cytosolic Translocation of the CD40 Complex To Regulate Downstream Signaling Pathways. | 32041822 |
| 2020-05-30 12:46:00 | The GSK3beta regulates Src phosphorylation via TNFR-associated factor 2 (TRAF2)-mediated Src ubiquitination. | 31619538 |
| 2020-05-23 12:47:00 | Striatal knockdown of TRAF2 increased infarction size, cell death, microglial activation and the expression of pro-inflammatory markers at 24 h after reperfusion. TRAF2 expression and necroptosis were induced in mouse primary microglia treated with conditioned medium collected from neurons subject to oxygen and glucose deprivation. | 30988281 |
| 2019-11-02 12:50:00 | Study findings demonstrate that RelB, involved in noncanonical NF-kappaB signaling, is upregulated by TRAF2 and is required for mediating the cytoprotective effects of TRAF2 overexpression in mouse model of myocardial infarction. Cytoprotective effects of TRAF2 are mediated by crosstalk between the canonical and noncanonical NF-kappaB signaling pathways, thereby revealing a complexity for NF-kappaB signaling in the heart. | 29415884 |
| 2019-08-17 10:09:00 | The results demonstrate that gp130-associated TRAF2 and TRAF5 inhibit the interaction between two JAK proteins in the IL-6R complex that is essential for initiating the signaling pathway. | 29668931 |
| Type | IDs |
|---|---|
| Synonymous | AI325259 |
| Gene |
UniProtKB-ID:
TRAF2_MOUSE,
Q3U8L1_MOUSE,
Q8C6X9_MOUSE
UniprotKB:
P39429,
Q3U8L1,
Q8C6X9
UniParc:
UPI00000E74C5,
UPI0000000A2B,
UPI00000E9AA6
EMBL:
AK151653,
AF233329,
AF233326,
AK052934,
AF233331,
AF233327,
AF233330,
AF233332,
AF027570,
AF233328,
BC003801,
AK152174,
L35303,
AL732590
Ensembl:
ENSMUSG00000026942
KO:
mmu:22030
|
| Nucleutide sequences |
EMBL-CDS:
AAH03801.1,
AAC37662.1,
AAC53545.1,
AAF59928.1,
BAE30582.1,
BAE31006.1,
BAC35209.1
Ensembl_TRS:
ENSMUST00000028311,
ENSMUST00000114234
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000109872,
ENSMUSP00000028311
RefSeq:
NP_033448.2,
XP_006497912.1,
NP_001277342.1,
XP_006497913.1
|
| Others |
UniRef100:
UniRef100_P39429,
UniRef100_Q8C6X9
UniRef90:
UniRef90_P39429
UniRef50:
UniRef50_Q12933
UniGene:
Mm.3399
CCDS:
CCDS15779.1,
CCDS71002.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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