| Type | Description |
|---|---|
| Definition | hepatic and glial cell adhesion molecule |
| Date | Results | Publications |
|---|---|---|
| 2020-06-27 11:53:00 | The heterozygous variant of the HEPACAM gene probably underlies the megalencephalic leukoencephalopathy with subcortical cyst in this child | 32335882 |
| 2020-03-21 12:13:00 | Six patients were clinically diagnosed with MLC. Of the six patients, five (Pt1-Pt5) presented with a heterozygous mutation in GLIALCAM (c.274C>T(p.Arg92Trp) or c.275G>C(p.Arg92Pro)) and were diagnosed with MLC2B; the remaining patient (Pt6) with two compound heterozygous mutations in GLIALCAM (c.203A>T (p.Lys68Met) and c.395C>A (p.Thr132Asn)) was diagnosed with MLC2A. The mutation c.275C>G (p.Arg92Pro) has not been repor | 31372844 |
| 2019-05-25 12:04:00 | The results suggest that HepaCAM and its cytoplasmic domain suppress the nuclear translocation of AR via Ran in prostate cancer (PCa). The cytoplasmic domain of HepaCAM may serve as a novel target for therapy in PCa. | 30664187 |
| 2018-10-06 10:04:00 | On the whole, this study indicates that HepaCAM potentially represents a therapeutic target and PF3084014 may prove to a promising agent for use in the treatment of refractory prostate cancer. | 29658567 |
| 2018-04-28 12:03:00 | hepaCAM associates with connexin 43, a main component of gap junctions, and enhances connexin 43 localization to the plasma membrane at cellular junctions. | 27819278 |
| Type | IDs |
|---|---|
| Synonymous | GlialCAM, HEPN1, MLC2A, MLC2B |
| Gene |
UniProtKB-ID:
HECAM_HUMAN
UniprotKB:
Q14CZ8
UniParc:
UPI0001596A0E,
UPI000013E4B5
EMBL:
BC104831,
AK122595,
AK098396,
AL834419,
AY047587,
BC113562
Ensembl:
ENSG00000165478
KO:
hsa:220296
|
| Nucleutide sequences |
EMBL-CDS:
AAQ93018.1,
AAI13563.1,
BAC85486.1,
CAD39081.1,
BAC05297.1,
AAI04832.1
Ensembl_TRS:
ENST00000298251
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000298251
RefSeq:
XP_016872850.1,
XP_005271506.1,
NP_689935.2
|
| Others |
UniRef100:
UniRef100_Q14CZ8
UniRef90:
UniRef90_Q14CZ8
UniRef50:
UniRef50_Q14CZ8
UniGene:
Hs.745294
CCDS:
CCDS8456.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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