| Type | Description |
|---|---|
| Definition | cysteine-rich secretory protein 2 |
| Date | Results | Publications |
|---|---|---|
| 2019-12-07 11:06:00 | we revealed a role for CRISP2 in establishing the ability of sperm to undergo the acrosome reaction and in establishing a normal flagellum waveform. Crisp2-deficient sperm possess a stiff midpiece and are thus unable to manifest the rapid form of progressive motility seen in wild type sperm. As a consequence, Crisp2-deficient males are subfertile. | 30759213 |
| 2016-12-17 12:06:00 | Crisp2 genetic defects in sperm from humans and mice result in male infertility. | 26786179 |
| 2010-02-22 12:16:00 | expression and localization of SHTAP in testis and sperm raise the possibility that the SHTAP-CRISP2 complex has a potential role in sperm formation and/or function. | 19686095 |
| 2010-01-21 00:00:00 | These data raise the possibility that CRISP2 is a MAP3K11-modifying protein or, alternatively, that MAP3K11 acts to phosphorylate CRISP2 during acrosome development. | 17377140 |
| 2010-01-21 00:00:00 | Evidence for a functional role of CRISP2 in fertilization. | 17202389 |
| Type | IDs |
|---|---|
| Synonymous | CRISP-2, GAPDL5, Tpx-1, Tpx1 |
| Gene |
UniProtKB-ID:
CRIS2_MOUSE
UniprotKB:
P16563
UniParc:
UPI00000221C4
EMBL:
M25533,
BC049615
Ensembl:
ENSMUSG00000023930
KO:
mmu:22024
|
| Nucleutide sequences |
EMBL-CDS:
AAH49615.1,
AAA40472.1
Ensembl_TRS:
ENSMUST00000024724,
ENSMUST00000233529,
ENSMUST00000232709
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000156411,
ENSMUSP00000156818,
ENSMUSP00000024724
RefSeq:
XP_006524099.1,
XP_030105504.1,
NP_001191000.1,
NP_033446.1
|
| Others |
UniRef100:
UniRef100_P16563
UniRef90:
UniRef90_P16563
UniRef50:
UniRef50_P12020
UniGene:
Mm.1296
CCDS:
CCDS28786.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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