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22021 Tpst1

22021

Tpst1

protein-tyrosine sulfotransferase 1

protein-coding

Mus musculus

基因描述

Type Description
Definition protein-tyrosine sulfotransferase 1

研究结论

Date Results Publications
2012-12-08 11:21:00 Results demonstrate the importance of protein-tyrosine sulfation for proper development of the retina and suggest different phenotypes resulting from elimination of TPST-1 or -2 may reflect differential expression patterns or levels of the enzymes. 22745813
2011-10-29 11:47:00 two genes identified in this analysis, PLEC1 and TPST1, reduced IL-6 production by macrophages 21665277
2011-10-01 12:07:00 Data show that Tpst1/Tpst2 DKO leukocytes bound less P-selectin than wild type leukocytes despite equivalent surface expression of Psgl-1. 21633705
2011-02-26 10:05:00 These results indicate that protein-tyrosine sulfation by Tpst1/2 is essential for proper outer segment morphogenesis and synaptic function, but is not critical for overall retinal structure or synapse formation. 21039965
2010-01-21 00:00:00 Tpst1 and Tpst2 are the only Tpst genes in mice, tyrosine sulfation is required for normal pulmonary function at birth, and TPST-2 is required for normal thyroid gland function. 18243191

名称对应

Type IDs
Synonymous R75054, Tango13a
Gene
UniProtKB-ID: TPST1_MOUSE, Q4FK50_MOUSE
UniprotKB: O70281, Q4FK50
UniParc: UPI000000191D
EMBL: BC012666, AK150753, CT010202, AF038008
Ensembl: ENSMUSG00000034118
KO: mmu:22021
Nucleutide sequences
EMBL-CDS: AAH12666.1, AAC13551.1, BAE29823.1, CAJ18410.1
Ensembl_TRS: ENSMUST00000040721, ENSMUST00000118993
Protein sequencees
Ensembl_PRO: ENSMUSP00000112571, ENSMUSP00000035614
RefSeq: XP_036020889.1, NP_001123948.1, XP_036020890.1, NP_038865.1, XP_006504481.1
Others
UniRef100: UniRef100_O70281
UniRef90: UniRef90_O60507
UniRef50: UniRef50_O60507
UniGene: Mm.332720
CCDS: CCDS39293.1

全选

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