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22019 Tpp2

22019

Tpp2

tripeptidyl peptidase II

protein-coding

Mus musculus

基因描述

Type Description
Definition tripeptidyl peptidase II

研究结论

Date Results Publications
2014-02-01 11:05:00 Data indicate that TPPII can regulate sperm maturation by modulating intracellular Ca(2+) stores via the type 3 RyR. 23818952
2013-04-06 12:19:00 Previously unknown differences between TPP II orthologues and subtilisin as well as features that might be conserved within the entire family of subtilisin-like serine peptidases. 22266401
2010-01-21 00:00:00 TPPII is not generally required for the production of major histocompatibility class I-restricted peptides, but presentation of some peptides can be negatively affected by TPPII. 17357105
2010-01-21 00:00:00 Data show that mice that were homozygous for an insertion in the Tpp2 locus were embryonic lethal and Tpp2 heterozygous mutants were lean compared with wild-type littermates, although food intake was normal. 17932511
2010-01-21 00:00:00 The data suggest a moderate, predominantly destructive role of TPPII in class I Ag processing. 18056356

名称对应

Type IDs
Synonymous TPP-2, TppII
Gene
UniProtKB-ID: TPP2_MOUSE
UniprotKB: Q64514
UniParc: UPI000002B5BE, UPI0000029D09
EMBL: BC058239, X81323
Ensembl: ENSMUSG00000041763
KO: mmu:22019
Nucleutide sequences
EMBL-CDS: CAA57103.1, AAH58239.1
Ensembl_TRS: ENSMUST00000188313, ENSMUST00000087933
Protein sequencees
Ensembl_PRO: ENSMUSP00000085244, ENSMUSP00000139918
RefSeq: NP_033444.1, NP_001297469.1
Others
UniRef100: UniRef100_Q64514
UniRef90: UniRef90_P29144
UniRef50: UniRef50_P29144
UniGene: Mm.401675
CCDS: CCDS14926.1, CCDS78577.1

全选

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研究热度

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