| Type | Description |
|---|---|
| Definition | docking protein 6 |
| Date | Results | Publications |
|---|---|---|
| 2010-07-05 11:19:00 | DOK-6 is involved in RET signaling with less influence when compared with DOK-1, DOK-4, and SHC. | 20210798 |
| 2010-06-30 22:05:00 | Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | 20379614 |
| 2010-01-21 00:00:00 | Dok-6 binds to the phosphorylated Ret Tyr(1062) residue resulting in phosphorylation of tyrosine residue(s) located within the unique C terminus of Dok-6 predominantly through a Src-dependent mechanism | 15286081 |
| Type | IDs |
|---|---|
| Synonymous | DOK5L, HsT3226 |
| Gene |
UniProtKB-ID:
DOK6_HUMAN
UniprotKB:
Q6PKX4
UniParc:
UPI000035EC7C
EMBL:
BC008583,
BC096744,
AC026585,
BC019045,
AK057795,
CH471117,
AY599248
Ensembl:
ENSG00000206052
KO:
hsa:220164
|
| Nucleutide sequences |
EMBL-CDS:
BAB71577.1,
AAH96744.1,
AAH08583.3,
AAH19045.2,
EAW66514.1,
AAT09770.1
Ensembl_TRS:
ENST00000382713
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000372160
RefSeq:
XP_011524177.1,
NP_689934.2,
XP_016881099.1,
XP_016881100.1
|
| Others |
UniRef100:
UniRef100_Q6PKX4
UniRef90:
UniRef90_Q6PKX4
UniRef50:
UniRef50_Q6PKX4
UniGene:
Hs.278285
CCDS:
CCDS32841.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32296183 |
A reference map of the human binary protein interactome. Nature Katja Luck , Dae-Kyum Kim , Luke Lambourne , Kerstin Spirohn , Bridget E Begg , Wenting Bian , Ruth Brignall , Tiziana Cafarelli , Francisco J Campos-Laborie , Benoit Charloteaux , Dongsic Choi , Atina G Coté , Meaghan Daley , Steven Deimling , Alice Desbuleux , Amélie Dricot , Marinella Gebbia , Madeleine F Hardy , Nishka Kishore , Jennifer J Knapp , István A Kovács , Irma Lemmens , Miles W Mee , Joseph C Mellor , Carl Pollis , Carles Pons , Aaron D Richardson , Sadie Schlabach , Bridget Teeking , Anupama Yadav , Mariana Babor , Dawit Balcha , Omer Basha , Christian Bowman-Colin , Suet-Feung Chin , Soon Gang Choi , Claudia Colabella , Georges Coppin , Cassandra D'Amata , David De Ridder , Steffi De Rouck , Miquel Duran-Frigola , Hanane Ennajdaoui , Florian Goebels , Liana Goehring , Anjali Gopal , Ghazal Haddad , Elodie Hatchi , Mohamed Helmy , Yves Jacob , Yoseph Kassa , Serena Landini , Roujia Li , Natascha van Lieshout , Andrew MacWilliams , Dylan Markey , Joseph N Paulson , Sudharshan Rangarajan , John Rasla , Ashyad Rayhan , Thomas Rolland , Adriana San-Miguel , Yun Shen , Dayag Sheykhkarimli , Gloria M Sheynkman , Eyal Simonovsky , Murat TaÅan , Alexander Tejeda , Vincent Tropepe , Jean-Claude Twizere , Yang Wang , Robert J Weatheritt , Jochen Weile , Yu Xia , Xinping Yang , Esti Yeger-Lotem , Quan Zhong , Patrick Aloy , Gary D Bader , Javier De Las Rivas , Suzanne Gaudet , Tong Hao , Janusz Rak , Jan Tavernier , David E Hill , Marc Vidal , Frederick P Roth , Michael A Calderwood |
2020-04-01 | - |
| 31343991 |
J. Clin. Invest. Pu Wang , Feng Yan , Zhijun Li , Yanbao Yu , Scott E Parnell , Yue Xiong |
2019-07-25 | - |
| 25416956 |
A proteome-scale map of the human interactome network. Cell Thomas Rolland , Murat TaÅan , Benoit Charloteaux , Samuel J Pevzner , Quan Zhong , Nidhi Sahni , Song Yi , Irma Lemmens , Celia Fontanillo , Roberto Mosca , Atanas Kamburov , Susan D Ghiassian , Xinping Yang , Lila Ghamsari , Dawit Balcha , Bridget E Begg , Pascal Braun , Marc Brehme , Martin P Broly , Anne-Ruxandra Carvunis , Dan Convery-Zupan , Roser Corominas , Jasmin Coulombe-Huntington , Elizabeth Dann , Matija Dreze , Amélie Dricot , Changyu Fan , Eric Franzosa , Fana Gebreab , Bryan J Gutierrez , Madeleine F Hardy , Mike Jin , Shuli Kang , Ruth Kiros , Guan Ning Lin , Katja Luck , Andrew MacWilliams , Jörg Menche , Ryan R Murray , Alexandre Palagi , Matthew M Poulin , Xavier Rambout , John Rasla , Patrick Reichert , Viviana Romero , Elien Ruyssinck , Julie M Sahalie , Annemarie Scholz , Akash A Shah , Amitabh Sharma , Yun Shen , Kerstin Spirohn , Stanley Tam , Alexander O Tejeda , Shelly A Trigg , Jean-Claude Twizere , Kerwin Vega , Jennifer Walsh , Michael E Cusick , Yu Xia , Albert-László Barabási , Lilia M Iakoucheva , Patrick Aloy , Javier De Las Rivas , Jan Tavernier , Michael A Calderwood , David E Hill , Tong Hao , Frederick P Roth , Marc Vidal |
2014-11-20 | - |
| 24483146 |
BMC Genomics Liang Li , Brooke L Fridley , Krishna Kalari , Nifang Niu , Gregory Jenkins , Anthony Batzler , Ryan P Abo , Daniel Schaid , Liewei Wang |
2014-02-01 | - |
| 20565848 |
BMC Biol Wei qi Li , Lei Shi , Yuan gang You , Yan hua Gong , Bin Yin , Jian gang Yuan , Xiao zhong Peng |
2010-06-18 | - |
| 20548944 |
PLoS Genet Yi-Hsiang Hsu , M Carola Zillikens , Scott G Wilson , Charles R Farber , Serkalem Demissie , Nicole Soranzo , Estelle N Bianchi , Elin Grundberg , Liming Liang , J Brent Richards , Karol Estrada , Yanhua Zhou , Atila van Nas , Miriam F Moffatt , Guangju Zhai , Albert Hofman , Joyce B van Meurs , Huibert A P Pols , Roger I Price , Olle Nilsson , Tomi Pastinen , L Adrienne Cupples , Aldons J Lusis , Eric E Schadt , Serge Ferrari , André G Uitterlinden , Fernando Rivadeneira , Timothy D Spector , David Karasik , Douglas P Kiel |
2010-06-10 | - |
| 20210798 |
Analysis of DOK-6 function in downstream signaling of RET in human neuroblastoma cells. Cancer Sci. Ai Kurotsuchi , Yoshiki Murakumo , Mayumi Jijiwa , Kei Kurokawa , Yasutomo Itoh , Yoshinori Kodama , Takuya Kato , Atsushi Enomoto , Naoya Asai , Hiroko Terasaki , Masahide Takahashi |
2010-05-01 |
DOK6,
RET
|
| 20379614 |
Mol. Med. Jed E Rose , Frédérique M Behm , Tomas Drgon , Catherine Johnson , George R Uhl |
2010-03-17 | - |
| 18187620 |
Identification of host proteins required for HIV infection through a functional genomic screen. Science Abraham L Brass , Derek M Dykxhoorn , Yair Benita , Nan Yan , Alan Engelman , Ramnik J Xavier , Judy Lieberman , Stephen J Elledge |
2008-02-15 |
gag,
gag-pol,
vif,
vpr,
tat,
rev,
vpu,
env,
nef,
MED6,
PIGK,
HUWE1,
PDIA6,
MPHOSPH6,
ADAM10,
RABEPK,
RRAGB,
ATG7,
ARPC1A,
POLR3F,
LEFTY1,
PNRC1,
TMED2,
PRDM7,
POLR3A,
ERI2,
SLC46A1,
SFT2D1,
GABARAPL2,
CARD16,
PKD1L2,
XKR4,
AGAP2,
AP2M1,
CLN3,
CLNS1A,
ERP27,
ANKRD9,
ZNF720,
RPTN,
ARHGEF19,
ZNF831,
C4orf33,
SOWAHA,
C9orf131,
RIMS4,
FAM76B,
ZNF785,
LYPD4,
PM20D1,
IQUB,
ZNF791,
DDOST,
DDX3X,
DMXL1,
DDX10,
TIMM8A,
DDX53,
EDNRA,
AGO3,
EGF,
EGFR,
CRTC2,
EPS8,
ERCC3,
AKT1,
AKT2,
ETF1,
DOK6,
C6orf1,
LNX2,
FHL3,
COG2,
TRAPPC8,
ANKRD6,
BAHD1,
FBXO21,
WDTC1,
FLII,
SEPT8,
MDN1,
OTUD3,
SCFD1,
NUP160,
FBXW11,
ARHGEF12,
FNTA,
PIP5K1C,
PHF3,
ETHE1,
TNPO3,
KLHDC2,
MKRN2,
COG4,
TRIM58,
INTS7,
SPATS2L,
GAPVD1,
RSL1D1
|
| 16273093 |
A quantitative protein interaction network for the ErbB receptors using protein microarrays. Nature Richard B Jones , Andrew Gordus , Jordan A Krall , Gavin MacBeath |
2006-01-12 |
SH2B3,
SH2D3A,
APBB3,
VAV3,
SH2B2,
CHN1,
CHN2,
CISH,
CLNK,
SH2D1B,
CRK,
CRKL,
DAB1,
DOK1,
EGFR,
ERBB2,
ERBB3,
ERBB4,
DOK6,
FER,
FES,
FGFR1,
FGR,
ANKS1A,
TNS2,
MAPK8IP2,
ABL1,
SHC2,
SH2B1,
APPL1,
DAPP1,
ABL2,
GRB2,
GRB7,
BLNK,
HCK,
APBB1,
APBB2,
IRS1,
ITK,
JAK1,
JAK2,
JAK3,
SH2D5,
SH2D1A,
MATK,
NCK1,
PIK3R1,
PIK3R2,
PLCG1,
SHC3,
PLCG2,
RIN2,
DOK4,
DOK5,
ANKS1B,
PTK6,
PTPN11,
RASA1,
BLK,
SH3BP2,
SHC1,
TNS3,
SLA,
BMX,
SRC,
STAT1,
STAT3,
SUPT6H,
SYK,
TEC,
TLN1,
TXK,
VAV1,
VAV2,
ZAP70,
BCAR3,
SLA2,
NCK2,
IRS4,
TNS4,
PIK3R3,
NUMB,
SOCS1,
SH2D2A,
NUMBL,
GRAP2,
MAPK8IP1,
APBA3,
RIN1
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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| 排名 | 研究人员 | 文献 |
|---|---|---|
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