| Type | Description |
|---|---|
| Definition | DNA damage induced apoptosis suppressor |
| Date | Results | Publications |
|---|---|---|
| 2019-03-09 10:56:00 | High DDIAS expression suppresses TRAIL-mediated apoptosis by inhibiting DISC formation and destabilizing caspase-8 in lung and liver cancer. | 29242605 |
| 2017-10-28 11:16:00 | these findings indicate that the stability of the DDIAS protein is regulated by CHIP/HSP70-mediated proteasomal degradation and that CHIP overexpression stimulates the apoptosis of lung cancer cells in response to DNA-damaging agents | 28079882 |
| 2017-07-22 13:56:00 | Noxin facilitated the expression of Cyclin D1 and Cyclin E1 through activating P38-activating transcription factor 2 signaling pathway, thus enhanced cell growth of breast cancer | 28618963 |
| 2017-07-01 11:44:00 | EGF activates the ERK5/MEF2 pathway, which in turn induces DDIAS expression to promote cancer cell invasion by activating beta-catenin target genes | 27412911 |
| 2016-04-30 11:11:00 | DDIAS is a target of NFATc1 and is associated with cisplatin resistance in lung cancer cells. | 26493727 |
| Type | IDs |
|---|---|
| Synonymous | C11orf82, noxin |
| Gene |
UniProtKB-ID:
DDIAS_HUMAN,
B4DMA1_HUMAN
UniprotKB:
Q8IXT1,
B4DMA1
UniParc:
UPI00017A75E5,
UPI00001AF966,
UPI00015F45F7
EMBL:
AK297366,
AK058145,
AP001646,
AK023998,
BC039268
Ensembl:
ENSG00000165490
KO:
hsa:220042
|
| Nucleutide sequences |
EMBL-CDS:
BAB71685.1,
BAB14764.1,
AAH39268.1,
BAG59813.1
Ensembl_TRS:
ENST00000533655,
ENST00000525361,
ENST00000329143
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000435421,
ENSP00000329930,
ENSP00000435424
RefSeq:
NP_659455.3,
XP_024304168.1,
NP_001350410.1,
XP_011543139.1,
XP_011543138.1
|
| Others |
UniRef100:
UniRef100_Q8IXT1
UniRef90:
UniRef90_Q8IXT1
UniRef50:
UniRef50_Q8IXT1
UniGene:
Hs.165607
CCDS:
CCDS8263.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员