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22003 Tpm1

22003

Tpm1

tropomyosin 1, alpha

protein-coding

Mus musculus

基因描述

Type Description
Definition tropomyosin 1, alpha

研究结论

Date Results Publications
2019-05-25 11:30:00 Tropomyosin pseudo-phosphorylation results in dilated cardiomyopathy. 30567734
2017-10-14 12:55:00 Stress fibre formation and up-regulation of alpha-smooth muscle actin (alphaSMA) induced by TGFbeta2 could be reversed by Tpm1/2 knock-down by siRNA. 27976512
2016-11-12 10:35:00 The cMyBP-C hypertrophic cardiomyopathy variant L348P enhances thin filament activation through an increased shift in tropomyosin position. 26718724
2015-03-28 11:11:00 three-dimensional structure of F-actin at a resolution of 3.7 A in complex with tropomyosin at a resolution of 6.5 A, determined by electron cryomicroscopy 25470062
2015-01-03 12:48:00 data also identify a novel alphaTM1/Tmod1-based pathway stabilizing F-actin at cell-cell junctions, which may be required for maintenance of cell shapes during embryonic cardiac morphogenesis. 24500875

名称对应

Type IDs
Synonymous AA986836, AI854628, TM2, TPM1kappa, Tm3, Tmpa, Tpm-1, alpha-TM
Gene
UniProtKB-ID: TPM1_MOUSE, B7ZNL3_MOUSE, E9Q452_MOUSE, A0A2R2Y2P8_MOUSE, Q8BP43_MOUSE, E9Q453_MOUSE, G5E8R1_MOUSE, G5E8R0_MOUSE, G5E8R2_MOUSE, E9Q454_MOUSE, E9Q455_MOUSE, Q545Y3_MOUSE, E9Q450_MOUSE, Q564G1_MOUSE, E9Q448_MOUSE
UniprotKB: P58771, B7ZNL3, E9Q452, A0A2R2Y2P8, Q8BP43, E9Q453, G5E8R1, G5E8R0, G5E8R2, E9Q454, E9Q455, Q545Y3, E9Q450, Q564G1, E9Q448
UniParc: UPI0000196429, UPI0000003E6E, UPI00000E6FF9, UPI0001548E64, UPI0000003E39, UPI000024EB4B, UPI0000170B52, UPI000024EE81, UPI000002B5AC, UPI000002B5AE, UPI0000F22412, UPI0000194445, UPI0000170B51, UPI00000EB110
EMBL: AK168783, BC145307, BC132037, M22479, X64831, AK169188, AK002271, AK168640, BC132035, AC166370, AK003175, AK077713, KY806114
Ensembl: ENSMUSG00000032366
KO: mmu:22003
Nucleutide sequences
EMBL-CDS: AAA40483.1, CAA46043.1, AAI45308.1, ATC20308.1, BAC36973.1, BAE40499.1, BAB21978.1, BAE40964.1, BAE40617.1, BAB22620.1, AAI32036.1, AAI32038.1
Ensembl_TRS: ENSMUST00000113707, ENSMUST00000113685, ENSMUST00000113705, ENSMUST00000113693, ENSMUST00000050905, ENSMUST00000113689, ENSMUST00000113695, ENSMUST00000113690, ENSMUST00000113696, ENSMUST00000113687, ENSMUST00000113686, ENSMUST00000113697, ENSMUST00000113701
Protein sequencees
Ensembl_PRO: ENSMUSP00000109337, ENSMUSP00000109315, ENSMUSP00000109335, ENSMUSP00000109323, ENSMUSP00000051888, ENSMUSP00000109319, ENSMUSP00000109325, ENSMUSP00000109320, ENSMUSP00000109326, ENSMUSP00000109317, ENSMUSP00000109316, ENSMUSP00000109327, ENSMUSP00000109331
RefSeq: NP_001157726.1, NP_001157727.1, NP_001157728.1, XP_030100100.1, XP_011241018.1, XP_006511114.1, NP_001157725.1, NP_001157723.1, XP_006511105.1, NP_077745.2, XP_030100101.1, NP_001157722.1, NP_001157720.1, XP_006511107.1, XP_006511103.1, XP_011241017.1, XP_006511112.1, XP_036010733.1, NP_001157724.1, XP_006511113.1, XP_006511104.1, XP_006511102.1, NP_001157721.1
Others
UniRef100: UniRef100_G5E8R2, UniRef100_E9Q454, UniRef100_G5E8R1, UniRef100_P58771, UniRef100_Q8BP43, UniRef100_E9Q452, UniRef100_E9Q450, UniRef100_G5E8R0, UniRef100_E9Q453, UniRef100_E9Q455, UniRef100_A0A2R2Y2P8, UniRef100_E9Q448, UniRef100_B7ZNL3, UniRef100_Q564G1
UniRef90: UniRef90_E9Q453, UniRef90_Q8BP43, UniRef90_B7ZNL3, UniRef90_G5E8R0, UniRef90_G5E8R2, UniRef90_Q923Z2, UniRef90_E9Q454, UniRef90_A0A2R2Y2P8, UniRef90_Q564G1, UniRef90_E9Q452, UniRef90_P58771, UniRef90_E9Q455, UniRef90_G5E8R1
UniRef50: UniRef50_P58771, UniRef50_A0A2R8YE05, UniRef50_Q63610, UniRef50_P04692-4, UniRef50_P09493, UniRef50_P04692-7
UniGene: Mm.121878
CCDS: CCDS52845.1, CCDS23311.1

全选

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