| Type | Description |
|---|---|
| Definition | von Willebrand factor C and EGF domains |
| Date | Results | Publications |
|---|---|---|
| 2019-08-03 11:13:00 | URG11 served an oncogenic role in the development of prostate cancer cells. | 30864678 |
| 2019-01-19 10:03:00 | URG11 is critical for the proliferation, migration, and invasion in prostate cancer cells | 29955600 |
| 2018-10-20 10:56:00 | silencing of URG11 altered the expression levels of cell cycleassociated genes, epithelialmesenchymal transitionassociated genes, and RhoA and ROCK1 protein levels. Thus, the results of the present study suggest that URG11 may be a potential therapeutic target, which may be important to inhibit the development and progression of prostatic hyperplasia. | 29749520 |
| 2017-03-18 10:31:00 | the study reported here provided evidence that URG11 downregulation suppresses proliferation, invasion, and beta-catenin expression in NSCLC cells. Our study uncovered a novel role for URG11 in NSCLC progression; thus, URG11 may be a novel potential therapeutic target for NSCLC. | 27458101 |
| 2016-03-12 10:54:00 | URG11 could promote hepatocellular carcinoma (HCC) cell growth and proliferation. It might play an important role in HCC development. | 26522362 |
| Type | IDs |
|---|---|
| Synonymous | URG11, VWC1 |
| Gene |
UniProtKB-ID:
VWCE_HUMAN
UniprotKB:
Q96DN2
UniParc:
UPI000013E751,
UPI000019B174
EMBL:
CH471076,
BC142624,
AY205235,
BC052564,
AK056571,
BC077719
Ensembl:
ENSG00000167992
KO:
hsa:220001
|
| Nucleutide sequences |
EMBL-CDS:
AAI42625.1,
AAO47606.1,
EAW73932.1,
BAB71219.1
Ensembl_TRS:
ENST00000301770,
ENST00000335613
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000301770,
ENSP00000334186
RefSeq:
XP_016872833.1,
XP_016872831.1,
XP_016872832.1,
NP_689931.2,
XP_006718523.1,
XP_006718525.1,
XP_011543119.1,
XP_016872830.1
|
| Others |
UniRef100:
UniRef100_Q96DN2
UniRef90:
UniRef90_Q96DN2
UniRef50:
UniRef50_Q96DN2
UniGene:
Hs.60640
CCDS:
CCDS8002.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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