例如:"NBL1", "4681", "drought"
收藏
219988 PATL1

219988

PATL1

PAT1 homolog 1, processing body mRNA decay factor

protein-coding

Homo sapiens

基因描述

Type Description
Definition PAT1 homolog 1, processing body mRNA decay factor

研究结论

Date Results Publications
2019-12-14 10:47:00 Another decapping activator PatL1 directly interacts with CIR and alleviates the CIR-mediated inhibition of CCR4-NOT activity in vitro. Ribosome profiling revealed that XRN1 loss impacts not only on mRNA levels but also on the translational efficiency of many cellular transcripts likely as a consequence of incomplete decay 31340047
2018-04-21 10:40:00 evidence for a nuclear complex of Pat1b with the Lsm2-8 heptamer, which binds to the spliceosomal U6 small nuclear RNA (snRNA). 28768202
2014-01-18 11:54:00 data indicate that P-body assembly occurs in a step-wise manner, where Rck participates in the initial suppression of mRNA translation, whereas Pat1b in a second step triggers P-body assembly and promotes mRNA decapping 23535175
2013-06-15 11:45:00 The PATL1 as well as DCP1A, a well-known P-body marker, co-localized with a subset of ALG-2. 22437941
2012-04-21 11:29:00 Pat1b participates in several RNA-related nuclear processes in addition to its multiple regulatory roles in the cytoplasm 22090346

名称对应

Type IDs
Synonymous Pat1b, hPat1b
Gene
UniProtKB-ID: PATL1_HUMAN
UniprotKB: Q86TB9
UniParc: UPI000007254F, UPI00001FA7D8, UPI0001F4E020, UPI0000072774
EMBL: BC109039, BC111047, AK094193, BC109038, AL831992, AB065087, AK127943, AP000640, BC065264, AP000442
Ensembl: ENSG00000166889
KO: hsa:219988
Nucleutide sequences
EMBL-CDS: AAI09039.1, BAG54601.1, AAI09040.1, BAC04305.1, AAI11048.1, BAB93524.1, AAH65264.2, CAD89916.1
Gene_ORFName: OK/KNS-cl.5
Ensembl_TRS: ENST00000300146
Protein sequencees
Ensembl_PRO: ENSP00000300146
RefSeq: NP_689929.2
Others
UniRef100: UniRef100_Q86TB9
UniRef90: UniRef90_Q86TB9
UniRef50: UniRef50_Q86TB9
UniGene: Hs.591960
CCDS: CCDS44613.1

全选

{{proteinIndex+1}}
mRNA Protein UniprotKB Description
Refseq {{protein.nucleotideVersion}}

Ensembl: {{protein.nucleotideEnsembl}}

{{protein.proteinVersion}}

Ensembl: {{protein.proteinEnsembl}}

{{uniprot}}
Definition: {{{protein.definition}}}

Transcript Veriant:{{protein.transcriptVeriant}}

Status: {{protein.status}}

Location ( {{protein.positionStart}}..{{protein.positionEnd}} )

暂无数据

研究热度

热点单位
排名 科研单位 文献
{{affIndex+1}}

{{aff.value}}

{{aff.size}}

目前还没有研究热点单位

热点人员
排名 研究人员 文献
{{authorIndex+1}}

{{author.value}}

{{author.size}}

目前还没有研究热点人员